GENERIC NAME: metaxalone
BRAND NAME: Skelaxin
DRUG CLASS AND MECHANISM: Metaxalone is an oral drug that relaxes skeletal muscle the muscles that control movement of the body. It does not act directly on skeletal muscle, and the exact mechanism of action of metaxalone is unknown. Metaxalone relaxes muscles possibly by affecting the central nervous system (brain and spinal cord) and by causing sedation. Metaxalone was approved by the FDA in 1962.
PRESCRIBED FOR: Metaxalone is used as an adjunct to physical therapy for treatment of short-term, painful muscle and skeletal conditions.
SIDE EFFECTS: The most common side effects with metaxalone are:
Other important, but less common, side effects include:
GENERIC AVAILABLE: Yes
PREPARATIONS: Tablets: 800 mg. STORAGE: Tablets should be stored at room temperature, 15-30 C (59-86 F).
DOSING: Metaxalone usually is taken at a dose of 800 mg, three or four times daily. Benefits are seen within one hour of ingestion. Food high in fat content increases the absorption of metaxalone.
DRUG INTERACTIONS: No important drug interactions have been described with metaxalone. Metaxalone may increase the sedative effects of alcohol and drugs that cause sedation, for example, benzodiazepines (Valium), antidepressants, opioids (morphine).
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