GENERIC NAME: MESORIDAZINE CONCENTRATE - ORAL (mezz-oh-RID-uh-zeen)
BRAND NAME(S): Serentil
Warning | Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage | Medical Alert
WARNING: Serious heart problems (QTc interval prolongation) have occurred in patients taking mesoridazine. QTc prolongation can infrequently result in serious, rarely fatal, irregular heartbeats. Consult your doctor or pharmacist for details. Ask for instructions about whether you need to stop any other QTc-prolonging drugs you may be using in order to minimize the risk of this effect. Mesoridazine should be used only when treatment with other drugs have failed.
USES: Mesoridazine is used to treat a mental/emotional condition (schizophrenia) that is untreatable with other drugs. It may be used for other conditions as determined by your doctor.
HOW TO USE: Take with food or milk if stomach upset occurs unless directed otherwise by your doctor. Your dosage is based on your condition and response to the medication. Take this medication exactly as prescribed. Do not increase your dose or stop taking this drug without first consulting your doctor. Measure carefully and dilute with 4 ounces or more of water, milk, juice or carbonated beverage. It can be mixed into applesauce or pudding. Do not dilute with coffee, tea, colas or apple juice because the medication may lose effectiveness. Take immediately after diluting. Do not dilute the drug and save for later use. It must be diluted before each dose. In the treatment of mental or emotional conditions, it may take up to two weeks for full benefit to be noticed.
SIDE EFFECTS: Constipation, drowsiness, vision changes, or dry mouth may occur. If any of these effects persist or worsen, notify your doctor. Tell your doctor immediately if any of these unlikely but serious side effects occur: dizziness, difficulty speaking, loss of balance, mask-like facial expression, trembling or shaking, lip smacking or other uncontrollable movements, difficulty urinating, skin rash/discoloration, muscle stiffness. Tell your doctor immediately if any of these highly unlikely but serious side effects occur: yellowing eyes or skin, vomiting, dark urine, hot dry skin, sore throat, stomach pain, unusual bleeding or bruising. Though highly unlikely to occur, notify your doctor immediately if you experience any of the following very serious side effects: fainting, irregular heartbeat, confusion, fever, seizures, severe muscle stiffness, increased sweating, prolonged/painful erection. In the unlikely event you have an allergic reaction to this drug, seek immediate medical attention. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Back to Medications Index