mesalamine, Pentasa, Rowasa, Asacol, Lialda, Canasa (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

Kidney dysfunction has been associated with mesalamine. Kidney function should be evaluated prior to and periodically during mesalamine therapy.

Mesalamine may cause an acute intolerance syndrome that resembles a flare of inflammatory bowel disease (Crohn's disease or ulcerative colitis) with cramping, abdominal pain, and bloody diarrhea. Fever, headache, itching, and rash also may occur. Symptoms usually subside once mesalamine is discontinued.

Mesalamine enemas contain sulfites and should be avoided in persons who are sensitive to sulfites.

Since mesalamine is related to aspirin in structure, individuals who are allergic to aspirin should not take mesalamine.

Reference: FDA Prescribing Information


Last Editorial Review: 3/26/2009



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