What is meropenem-injection, and how does it work (mechanism of action)?

Meropenem is an injectable carbapenem antibiotic. It is similar to impenem and cilastin (Primaxin). Meropenem prevents bacteria from forming the walls that surround them. The walls are necessary to protect bacteria from their environment and to keep the contents of the bacterial cell together. Bacteria cannot survive without a cell wall. Meropenem is effective against susceptible strains of E. coli, H. influenzae, K. pneumoniae, N. meningitidis, P. aeruginosa, and many other bacteria.

The FDA approved meropenem in June 1996.

What brand names are available for meropenem-injection?

Merrem

Is meropenem-injection available as a generic drug?

GENERIC AVAILABLE: Yes

Do I need a prescription for meropenem-injection?

Yes

What are the side effects of meropenem-injection?

Common side effects of meropenem are:

Injection site pain and inflammation

• Rash
• Constipation
• Diarrhea
• Nausea
• Vomiting
• Headache

Serious reactions rarely may occur such as:

• Cardiovascular arrest
• Bowel obstruction
• Kidney failure
• Seizures

Serious hypersensitivity (allergic) reactions may occur.

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Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.