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mercaptopurine - oral, Purinethol (cont.)

PRECAUTIONS: Before taking mercaptopurine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.This medication should not be used if you have a certain medical condition. Before taking this medicine, consult your doctor or pharmacist if a certain drug (thioguanine) did not work for you in the past. This may affect how well mercaptopurine works for you.Before using this medication, tell your doctor or pharmacist your medical history, especially of: other blood disorders (e.g., anemia, low blood cell counts), gout, kidney disease (including kidney stones), liver disease, pancreatitis, radiation treatment, history of cancer (such as lymphoma).Do not have immunizations/vaccinations without the consent of your doctor, and avoid contact with people who have recently received oral polio vaccine or flu vaccine inhaled through the nose.Wash your hands well to prevent the spread of infections.To lower your risk of getting cut, bruised, or injured, use caution with sharp objects like razors and nail cutters, and avoid activities such as contact sports.If you need to have surgery or a dental procedure, tell your doctor or dentist that you are using mercaptopurine.Drinking alcohol may increase the risk of stomach/esophageal irritation or liver damage. Limit alcoholic beverages.People with a certain inherited problem (lack of thiopurine methyltransferase-TPMT enzyme) may be at increased risk for serious side effects from this medication and may require dosage adjustment. Consult your doctor for details and to discuss whether you should be tested for this inherited problem.Caution is advised when using this drug in the elderly because they may be more sensitive to the effects of the drug, especially the liver and bone marrow effects.This medication is not recommended for use during pregnancy. It may harm the unborn baby. It may be particularly harmful during the first 3 months of pregnancy. Consult your doctor for more details and to discuss reliable forms of birth control. If you become pregnant or think you may be pregnant, tell your doctor immediately.It is not known whether this drug passes into breast milk. Because of the possible risk to the infant, breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding.

Medically Reviewed by a Doctor on 4/16/2014


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