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March 19, 2010
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GENERIC NAME: MERCAPTOPURINE - ORAL (mer-CAP-toe-pure-een)

BRAND NAME(S): Purinethol

Medication Uses | Other Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage | Medical Alert

USES: Mercaptopurine is used to treat leukemia. It is also used for pediatric non-Hodgkin's lymphoma, polycythemia vera, and psoriatic arthritis.

OTHER USES: This medication may also be used for inflammatory bowel disease.

HOW TO USE: This is a potent medication. Take it exactly as prescribed. Unless your doctor instructs you otherwise, drink plenty of fluids to avoid dehydration. Contact your doctor if you vomit shortly after taking your dose.

SIDE EFFECTS: Diarrhea, nausea, vomiting, loss of appetite, stomach/abdominal pain, weakness, skin rash, darkening of the skin, or hair loss may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Tell your doctor immediately if any of these serious side effects occur: mouth sores, fever, sore throat, easy bruising or bleeding, pinpoint red spots on the skin, yellowing of eyes or skin, dark urine, painful or difficult urination. Tell your doctor immediately if any of these unlikely but serious side effects occur: black or tarry stools, blood in urine or stool. An allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.




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mercaptopurine-oral, Purinethol

What is leukemia?

Leukemia is cancer that starts in the tissue that forms blood. To understand cancer, it helps to know how normal blood cells form.

Normal Blood Cells

Most blood cells develop from cells in the bone marrow called stem cells. Bone marrow is the soft material in the center of most bones.

Stem cells mature into different kinds of blood cells. Each kind has a special job:


White blood cells help fight infection. There are several types of white blood cells.


Red blood cells carry oxygen to tissues throughout the body.


Platelets help form blood clots that control bleeding.

White blood cells, red blood cells, and platelets are made from stem cells as the body needs them. When cells grow old or get damaged, they die, and new cells take their place.

The picture below shows how stem cells can mature into different types of white blood c...

Read the Leukemia article »




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