meloxicam, Mobic (cont.)

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Medical and Pharmacy Editor:

Meloxicam oral suspension contains sorbitol. Combining sodium polystyrene sulfonate (Kayexalate) with sorbitol may cause fatal intestinal necrosis. Therefore, meloxicam oral solution should not be combined with Kayexalate.

PREGNANCY: There have been no studies of meloxicam therapy in pregnant women. Meloxicam generally should be avoided during the first and second trimester of pregnancy. Since meloxicam may cause a fetal birth defect called ductus arteriosus (early closure of two major blood vessels of the heart and lung) in the third trimester of pregnancy, meloxicam also should be avoided during this last part of pregnancy.

NURSING MOTHERS: There have been no studies in humans to determine if meloxicam is excreted in breast milk.

SIDE EFFECTS: In general, the most common side effects with NSAIDs are related to the gastrointestinal tract (GI) and include nausea, vomiting, abdominal pain, diarrhea, and gas. To prevent these common side effects, it is recommended that most NSAIDs be taken with food or milk. NSAIDs may cause ulcers in the stomach and/or small intestine. A few NSAIDs are designed to be less damaging to the stomach and small intestine, and, therefore, they may be taken with or without food. Meloxicam is an example of one of these NSAIDs, but, nevertheless, it should be taken cautiously without food. NSAIDs have been associated with an increased risk of blood clots that can cause strokes and heart attacks. NSAIDs also may interfere with the function of the kidneys or injure the kidneys.

Other less common side effects of meloxicam are headache, fatigue related to anemia (low red blood cell count), joint pain, back pain, insomnia, itching, skin rash, bladder infection and upper respiratory tract infection.

Reference: FDA Prescribing Information

Medically Reviewed by a Doctor on 10/11/2013

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