Melioidosis
(Whitmore's Disease)
Medical Author: John P. Cunha, DO
Medical Editor: William C. Shiel Jr., MD, FACP, FACR
What is melioidosis? What causes melioidosis?
Melioidosis, also called Whitmore's Disease, is an infectious disease caused by
a bacterium called Burkholderia pseudomallei (previously known as Pseudomonas pseudomallei). The bacteria are found in contaminated water and soil and spread to humans and animals through direct contact with the contaminated source. The bacteria are also of some concern as a potential agent for biological warfare and biological terrorism.
Melioidosis is similar to glanders disease, which is passed to humans from infected domestic animals.
Where does melioidosis occur?
Melioidosis is most frequently reported in Southeast Asia and Northern Australia. It also occurs in South Pacific, Africa, India, and the Middle East. The bacterium that causes the disease is found in the soil, rice paddies, and stagnant waters of the area. People acquire the disease by inhaling dust contaminated by the bacteria and when the contaminated soil comes in contact with abraded (scraped) area of the skin. Infection most commonly occurs during the rainy season.
In the United States, confirmed cases range from none to five each year and occur among travelers and immigrants, according to the U.S. Centers for Disease Control and Prevention (CDC).
What are symptoms of melioidosis?
Melioidosis symptoms most commonly stem from lung disease where the infection can form a cavity of pus (abscess). The effects can range from mild bronchitis to severe pneumonia. As a result, patients also may experience fever, headache, loss of appetite, cough, chest pain, and general muscle soreness.
The effects can also be localized to infection on the skin (cellulitis) with associated fever and muscle aches. It can spread from the skin through the blood to become a chronic form of melioidosis affecting the heart, brain, liver, kidneys, joints, and eyes.
Melioidosis can be spread from person to person as well.
Next: How is melioidosis diagnosed? »
- doxycycline, Vibramycin, Oracea, Adoxa, Atridox and Others - Learn more about Doxycycline, including a description, generic and brand names, drug class and mechanism, preparations, storage, reasons for prescription, dosing, drug interactions, effect on pregnancy and nursing mothers, and common side effects.
- Chest X-ray - A chest x-ray is a radiology test that involves exposing the chest briefly to radiation to produce an image of the chest and the internal organs of the chest. chest x-ray can be used to define abnormalities of the lungs such as excessive fluid, pneumonia, bronchitis, asthma, cysts, and cancers.
- Pneumonia - Learn pneumonia symptoms, causes, treatment, signs, diagnosis and types: viral and bacterial (Pneumocystis carinii, Klebsiella, Mycoplasma, Chlamydia pneumoniae).
Latest Medical News
Specialty RSS
