Melatonin (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

PRESCRIPTION: No

GENERIC AVAILABLE: Yes

PREPARATIONS: Melatonin is available in 1 mg, 3 mg, 5 mg, and 10 mg strengths. Melatonin is available in tablets, capsules, chewable gummies, sublingual tablets, and in liquid form.

STORAGE: Melatonin is usually stored at room temperature.

DOSING:

  • Sleeplessness, sleep-wake cycle changes: Take 0.3 to 5 mg by mouth daily at bedtime.
  • Migraine headaches: Take 3 to 10 mg by mouth daily at bedtime.

DRUG INTERACTIONS: Melatonin should be used with caution with birth control medications and fluvoxamine (Luvox) because they increase melatonin levels in the body and cause increased sedation.

Melatonin should be used with caution with medications like zolpidem (Ambien), alprazolam (Xanax), clonazepam (Klonopin), diazepam (Valium), and zalepon (Sonata) because they cause increased sedation.

Melatonin should be used with caution with medications like aspirin, heparin, warfarin (Coumadin), clopidogrel (Plavix), diclofenax (Voltaren), and meloxicam (Mobic) because they increase the risk of bleeding and bruising.

PREGNANCY: There are no adequate studies done on melatonin to determine safe and effective use in pregnant women.

NURSING MOTHERS: It is not known whether melatonin enters breast milk. It is best for nursing mothers to avoid using melatonin.

REFERENCE:

Medscape: Melatonin (Herbs/Suppl) N-acetyl-5-methoxytryptamine, pineal hormone


Medline Plus, National Library of Medicine
http://nccam.nih.gov/health/melatonin


Medically Reviewed by a Doctor on 10/10/2014


Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Pill Finder Tool

Need help identifying pills and medications?
Use the pill identifier tool on RxList.


Back to Medications Index