Melatonin

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Charles Patrick Davis, MD, PhD
    Charles Patrick Davis, MD, PhD

    Charles Patrick Davis, MD, PhD

    Dr. Charles "Pat" Davis, MD, PhD, is a board certified Emergency Medicine doctor who currently practices as a consultant and staff member for hospitals. He has a PhD in Microbiology (UT at Austin), and the MD (Univ. Texas Medical Branch, Galveston). He is a Clinical Professor (retired) in the Division of Emergency Medicine, UT Health Science Center at San Antonio, and has been the Chief of Emergency Medicine at UT Medical Branch and at UTHSCSA with over 250 publications.

Insomnia Pictures: 10 Tips to Avoid Insomnia

What is melatonin-oral, and how does it work (mechanism of action)?

Melatonin is a natural hormone produced by the pineal gland in the body. Commercially available melatonin that is sold as medicine is produced in the laboratory. Melatonin regulates sleep-wake cycle. Check with your healthcare professional before using herbs or other supplements.

What brand names are available for melatonin-oral?

N/A

Is melatonin-oral available as a generic drug?

GENERIC AVAILABLE: Yes

Do I need a prescription for melatonin-oral?

No

What are the uses for melatonin-oral?

Melatonin is used for sleeplessness and adjusting sleep-wake cycles due to jet lag or work schedule changes.

Melatonin is also used for treatment of:

What are the side effects of melatonin-oral?

Side effects of melatonin are:

What is the dosage for melatonin-oral?

  • Sleeplessness, sleep-wake cycle changes: Take 0.3 to 5 mg by mouth daily at bedtime.
  • Migraine headaches: Take 3 to 10 mg by mouth daily at bedtime.

Which drugs or supplements interact with melatonin-oral?

Melatonin should be used with caution with birth control medications and fluvoxamine (Luvox) because they increase melatonin levels in the body and cause increased sedation.

Melatonin should be used with caution with medications like:

These drugs cause increased sedation.

Melatonin should be used with caution with medications like:

These drugs increase the risk of bleeding and bruising.

Is melatonin-oral safe to take if I'm pregnant or breastfeeding?

There are no adequate studies done on melatonin to determine safe and effective use in pregnant women.

It is not known whether melatonin enters breast milk. It is best for nursing mothers to avoid using melatonin.

What else should I know about melatonin-oral?

What preparations of melatonin-oral are available?

Melatonin is available in 1 mg, 3 mg, 5 mg, and 10 mg strengths. Melatonin is available in tablets, capsules, chewable gummies, sublingual tablets, and in liquid form.

How should I keep melatonin-oral stored?

Melatonin is usually stored at room temperature.

REFERENCE:

Medscape: Melatonin (Herbs/Suppl) N-acetyl-5-methoxytryptamine, pineal hormone


Medline Plus, National Library of Medicine
http://nccam.nih.gov/health/melatonin

Last Editorial Review: 7/1/2016

Subscribe to MedicineNet's Depression Newsletter

By clicking Submit, I agree to the MedicineNet's Terms & Conditions & Privacy Policy and understand that I may opt out of MedicineNet's subscriptions at any time.

FDA Logo

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Reviewed on 7/1/2016
References
REFERENCE:

Medscape: Melatonin (Herbs/Suppl) N-acetyl-5-methoxytryptamine, pineal hormone


Medline Plus, National Library of Medicine
http://nccam.nih.gov/health/melatonin

Health Solutions From Our Sponsors