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- Patient Comments: MELAS Syndrome - Symptoms
- Patient Comments: MELAS Syndrome - Treatment
- Patient Comments: MELAS Syndrome - When Symptoms Develop
How is MELAS treated?
There is no known treatment for the underlying disease, which is progressive and fatal. Patients are managed according to what areas of the body are affected at a particular time. antioxidants and vitamins have been used, but there have been no consistent successes reported.
Are there other mitochondrial diseases?
Yes, mutations (genetic changes) in the mitochondrial chromosome are responsible for a number of other disorders aside from MELAS such as:
- an important eye disease called Leber hereditary optic atrophy;
- a type of epilepsy called MERRF which stands for Myoclonus Epilepsy with Ragged Red Fibers; and
- a neuromuscular disease called the Kearns-Sayre syndrome.
MELAS and all other mitochondrial diseases were not well understood before it was discovered that they were due to mutations in the chromosomes of the mitochondria.
Medically reviewed by Joseph Carcione, DO; American Board of Psychiatry and Neurology
"Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes"
National Institutes of Health