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Melanosis Coli Center - Wilmington, NC

Wilmington Gastroenterologist Doctors for Melanosis Coli

Type of Physician: Gastroenterologist

What is a Gastroenterologist?

A subspecialty certification by the Board of Internal Medicine; practitioners focus on the stomach, intestines, colon, liver, and gallbladder (digestive organs). The gastroenterologist treats conditions such as abdominal pain, ulcers, diarrhea, cancer, and jaundice and they consult with surgeons when abdominal operations are indicated.

Specialty: Gastroenterology

Common Name: GI Doctor

Gastroenterologist Doctors in Wilmington *

Hanover Medical Specialists PA Gastroenterology
Kevin Gaylord
1515 Doctors Cir
Bldg B
Wilmington, NC 28401
(910) 763-1219

Hanover Medical Specialists PA Gastroenterology
William A Gramley
1515 Doctors Cir
Bldg B
Wilmington, NC 28401
(910) 763-1219

Hanover Medical Specialists PA Gastroenterology
Michael R Mastrangelo
1515 Doctors Cir
Bldg B
Wilmington, NC 28401
(910) 763-1219

Hanover Medical Specialists PA Gastroenterology
James M Mertesdorf
1515 Doctors Cir
Bldg B
Wilmington, NC 28401
(910) 763-1219

Hanover Medical Specialists PA Gastroenterology
Frederick H Opper
1515 Doctors Cir
Bldg B
Wilmington, NC 28401
(910) 763-1219

Wilmington Gastroenterology Associates
D Spencer Carney
5115 Oleander Dr
Wilmington, NC 28403
(910) 362-1011

Wilmington Gastroenterology Associates
Robert D Henihan
5115 Oleander Dr
Wilmington, NC 28403
(910) 362-1011

Wilmington Gastroenterology Associates
William W King
5115 Oleander Dr
Wilmington, NC 28403
(910) 362-1011

Wilmington Gastroenterology Associates
Joseph W Kittinger
5115 Oleander Dr
Wilmington, NC 28403
(910) 362-1011

Wilmington Gastroenterology Associates
Steven Klein
5115 Oleander Dr
Wilmington, NC 28403
(910) 362-1011

Wilmington Gastroenterology Associates
Clinton L Meyer
5115 Oleander Dr
Wilmington, NC 28403
(910) 362-1011

Wilmington Gastroenterology Associates
Mariam Sauer
5115 Oleander Dr
Wilmington, NC 28403
(910) 362-1011

Coastal Gastroenterology
Frank L Holt
3 Medical Center Dr
Supply, NC 28462
(910) 754-7790

Jacksonville Digestive Disease Clinic
Mahmoud A Issa
224 Memorial Dr
STE STE A
Jacksonville, NC 28540
(910) 577-1444

East Carolina Gastroenterology PA
Peter A Eweje
4 Office Park Dr
Jacksonville, NC 28546
(910) 353-6158

Kinston Digestive Diseases
Richard James Kroeger
1100 Hardee Rd
STE 103B
Kinston, NC 28504
(252) 522-0285

Eastern Carolina Internal Medicine
Wendy P Moeller
137 Medical Ln
Pollocksville, NC 28573
(252) 638-4023

Joseph A Saracino MD
Joseph A Saracino
2602 N Heritage St
Kinston, NC 28501
(252) 527-6565

Kinston Medical Specialists
Robert T Dickson
701 Doctors Dr
STE N
Kinston, NC 28501
(252) 559-2200

Ikechukwu Ibegbu MD
Ikechukwu E Ibegbu
111 Airport Rd
Kinston, NC 28501
(252) 527-2390

Southeastern Gastroenterology
Santhosh Augustine
101 W 27th St
Lumberton, NC 28358
(910) 739-0770

Digestive Disease Center
V C Motaparthy
2705 Medical Office Pl
Goldsboro, NC 27534
(919) 731-2526

Southern Gastroenterology
David B Byrd
3100 Wellons Blvd
New Bern, NC 28562
(252) 634-9000

Southern Gastroenterology
William Stewart Futch
3100 Wellons Blvd
New Bern, NC 28562
(252) 634-9000

Southern Gastroenterology
Joseph Healy
3100 Wellons Blvd
New Bern, NC 28562
(252) 634-9000

Eastern Carolina Internal Medicine
Paul Tourigny
2604 Martin Luther King Jr Blvd
New Bern, NC 28562
(252) 633-1010

Fayetteville Gastroenterology Associates
Anthony Daniels
2041 Valley Gate Dr
Fayetteville, NC 28304
(910) 323-5203

Fayetteville Gastroenterology Associates
John R Jones
2041 Valley Gate Dr
Fayetteville, NC 28304
(910) 323-5203

Fayetteville Gastroenterology Associates
Valli P Kodali
2041 Valley Gate Dr
Fayetteville, NC 28304
(910) 323-5203

Fayetteville Gastroenterology Associates
Arvind H Kumar
2041 Valley Gate Dr
Fayetteville, NC 28304
(910) 323-5203

Fayetteville Gastroenterology Associates
John Poulos
2041 Valley Gate Dr
Fayetteville, NC 28304
(910) 323-5203

Fayetteville Gastroenterology Associates
William F VorderBruegge
2041 Valley Gate Dr
Fayetteville, NC 28304
(910) 323-5203

Fayetteville Gastroenterology Associates
Dimiter Zafirov
2041 Valley Gate Dr
Fayetteville, NC 28304
(910) 323-5203

Cape Fear Center for Digestive Diseases PA
Christian Y Chung
1880 Quiet Cove
Fayetteville, NC 28304
(910) 323-2477

Cape Fear Center for Digestive Diseases PA
Rakesh Gupta
1880 Quiet Cove
Fayetteville, NC 28304
(910) 323-2477

Cape Fear Center for Digestive Diseases PA
John W Jones
1880 Quiet Cove
Fayetteville, NC 28304
(910) 323-2477

Cape Fear Center for Digestive Diseases PA
Sanjeev Slehria
1880 Quiet Cove
Fayetteville, NC 28304
(910) 323-2477

Cape Fear Center for Digestive Diseases PA
Bryan D Uslick
1880 Quiet Cove
Fayetteville, NC 28304
(910) 323-2477

Owen Drive Surgical
F Andrew Morfesis
513 Owen Dr
Fayetteville, NC 28304
(910) 323-0101

Dunn Gastroenterology
Indira M Reddy
861 Tilghman Dr
STE 103
Dunn, NC 28334
(910) 891-1111

Johnston Gastroenterology
Christopher Jordan
415 N 7th St
STE C
Smithfield, NC 27577
(919) 938-4404

Neuse Gastroenterology PA
Richard S Lee
709 North St
Smithfield, NC 27577
(919) 934-6110

Wilmington, North Carolina

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Melanosis Coli

What is melanosis coli?

Melanosis coli is a condition usually associated with chronic laxative use in which dark pigment is deposited in the lamina propria (one of the lining layers) of the large intestine (colon). The pigment deposition results in a characteristic dark brown to black discoloration of the lining of the large intestine. This condition is sometimes called pseudomelanosis coli because the pigment deposits consist of a pigment known as lipofuscin and do not contain melanin as implied by the term "melanosis." Lipofuscin is a cellular pigment that forms when cells are destroyed, often called "wear and tear" pigment that can be found throughout the body.

The dark color of the intestinal lining may be uniform or patterned, and the discoloration may be slight or very pronounced. The intensity and pattern of the discoloration may even vary among different sites in the colon of a patient. The condition may also be reversed upon discontinuation of laxative use. In some cases, the wall of the colon appears normal to the eye, but microscopic evaluation of biopsies by a pathologist reveals areas of pigment in the colon's lining. The pigment in melanosis coli does not accumulate in polyps or tumors of the large intestine.

What are the symptoms of melanosis coli?

Melanosis coli does not cause symptoms.

What causes melanosis coli?

Melanosis coli usually results from chronic use of laxatives of the anthranoid group. Some examples of anthranoid laxatives are senna and rhubarb derivatives. Many of these laxatives have been in use for hundreds of years. In 1997, the U.S. Food and Drug Administration (FDA) banned the use of the popular anthranoid laxative phenolphthalein due to fears that it might be carcinogenic (cancer-causing). Animal studies had shown that extremely high doses of phenolphthalein led to tumors in animals, but it has nev...

Recommended Reading Related to Melanosis Coli

Flexible Sigmoidoscopy »

What is flexible sigmoidoscopy?

Flexible sigmoidoscopy is a procedure that allows your doctor to examine the rectum and the lower (sigmoid) colon. The flexible sigmoidoscope is a flexible tube 60 cm long and about the thickness of your little finger. It is inserted gently into the anus and advanced slowly into the rectum and the lower colon. It is an accurate and simple method of investigating the cause of rectal bleeding, change in bowel habit, and rectal symptoms such as pain and diarrhea. Flexible sigmoidoscopy also is a part of colon screening and surveillance for colon cancer.

What is the preparation for flexible sigmoidoscopy?

In order to obtain accurate results, the rectum and the lower colon must be completely clean of stool. Your doctor will give you detailed instructions on how to cleanse your colon. In general, this requires the use of one or two enemas prior to the procedure and may also call for a laxative and some dietar...

Emergency Contact for Wilmington

  • In case of Emergency, call 911

Nearby Wilmington Hospitals *

New Hanover Regional Medical Center
2131 S 17th St
Wilmington, NC 28401
(910)343-7000

Cape Fear Hospital
5301 Wrightsville Ave
Wilmington, NC 28403
(910)452-8100

Dosher Memorial Hospital
924 N Howe St
Southport, NC 28461
(910)457-3800

Pender Memorial Hospital
507 E Freemont St
Burgaw, NC 28425
(910)259-5451

Brunswick Community Hospital
1 Medical Center Dr
Supply, NC 28462
(910)755-8121

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