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Melanosis Coli Center - Sioux Falls, SD

Sioux Falls Gastroenterologist Doctors for Melanosis Coli

Type of Physician: Gastroenterologist

What is a Gastroenterologist?

A subspecialty certification by the Board of Internal Medicine; practitioners focus on the stomach, intestines, colon, liver, and gallbladder (digestive organs). The gastroenterologist treats conditions such as abdominal pain, ulcers, diarrhea, cancer, and jaundice and they consult with surgeons when abdominal operations are indicated.

Specialty: Gastroenterology

Common Name: GI Doctor

Gastroenterologist Doctors in Sioux Falls *

Sanford Clinic Gastroenterology
Jorge A Gilbert
1201 S Euclid Ave
STE 104
Sioux Falls, SD 57105
(605) 328-8500

Sanford Clinic Gastroenterology
Christopher M Hurley
1201 S Euclid Ave
STE 104
Sioux Falls, SD 57105
(605) 328-8500

Gastroenterology
Robert D Meyer
1200 S Euclid Ave
STE 210
Sioux Falls, SD 57105
(605) 335-1500

Sanford Clinic Gastroenterology
Jeffrey A Murray
1201 S Euclid Ave
STE 104
Sioux Falls, SD 57105
(605) 328-8500

Sanford Clinic Gastroenterology
JoAnn E Ormand
1201 S Euclid Ave
STE 104
Sioux Falls, SD 57105
(605) 328-8500

Sanford Clinic Gastroenterology
Tim M Ridgway
1201 S Euclid Ave
STE 104
Sioux Falls, SD 57105
(605) 328-8500

Sanford Clinic Gastroenterology
Troy D Schmidt
1201 S Euclid Ave
STE 104
Sioux Falls, SD 57105
(605) 328-8500

Sanford Clinic Gastroenterology
Philip E Tanner
1201 S Euclid Ave
STE 104
Sioux Falls, SD 57105
(605) 328-8500

Sioux Falls Gastroenterology
John D Barker
1001 E 21st St
STE 501
Sioux Falls, SD 57105
(605) 322-8630

Sioux Falls Gastroenterology
Shamoun Dany
1001 E 21st St
STE 501
Sioux Falls, SD 57105
(605) 322-8630

Midwest Medical Center
Chandar Singaram
1905 W 57th St
STE 1
Sioux Falls, SD 57108
(605) 310-2000

Yankton Medical Clinic
Steve Gutnik
1104 W 8th St
Yankton, SD 57078
(605) 665-7841

Sioux Falls, South Dakota

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Melanosis Coli

What is melanosis coli?

Melanosis coli is a condition usually associated with chronic laxative use in which dark pigment is deposited in the lamina propria (one of the lining layers) of the large intestine (colon). The pigment deposition results in a characteristic dark brown to black discoloration of the lining of the large intestine. This condition is sometimes called pseudomelanosis coli because the pigment deposits consist of a pigment known as lipofuscin and do not contain melanin as implied by the term "melanosis." Lipofuscin is a cellular pigment that forms when cells are destroyed, often called "wear and tear" pigment that can be found throughout the body.

The dark color of the intestinal lining may be uniform or patterned, and the discoloration may be slight or very pronounced. The intensity and pattern of the discoloration may even vary among different sites in the colon of a patient. The condition may also be reversed upon discontinuation of laxative use. In some cases, the wall of the colon appears normal to the eye, but microscopic evaluation of biopsies by a pathologist reveals areas of pigment in the colon's lining. The pigment in melanosis coli does not accumulate in polyps or tumors of the large intestine.

What are the symptoms of melanosis coli?

Melanosis coli does not cause symptoms.

What causes melanosis coli?

Melanosis coli usually results from chronic use of laxatives of the anthranoid group. Some examples of anthranoid laxatives are senna and rhubarb derivatives. Many of these laxatives have been in use for hundreds of years. In 1997, the U.S. Food and Drug Administration (FDA) banned the use of the popular anthranoid laxative phenolphthalein due to fears that it might be carcinogenic (cancer-causing). Animal studies had shown that extremely high doses of phenolphthalein led to tumors in animals, but it has nev...

Recommended Reading Related to Melanosis Coli

Constipation »

Constipation facts

  • Constipation is defined medically as fewer than three stools per week and severe constipation as less than one stool per week.
  • Constipation usually is caused by the slow movement of stool through the colon.
  • There are many causes of constipation including medications, poor bowel habits, low fiber diets, abuse of laxatives, hormonal disorders, and diseases primarily of other parts of the body that also affect the colon.
  • The two disorders limited to the colon that cause constipation are colonic inertia and pelvic floor dysfunction.
  • Medical evaluation for the cause of constipation should be done when constipation is of sudden onset, severe, worsening, associated with other worrisome symptoms such as loss of weight, or is not responding to simple, safe treatments.
  • Medical evaluation of constipation may include a history, physical examinatio...

Emergency Contact for Sioux Falls

  • In case of Emergency, call 911

Nearby Sioux Falls Hospitals *

Avera McKennan Hospital & University Health Center
800 E 21st St
Sioux Falls, SD 57117
(605)322-8000

Select Specialty Hospital Sioux Falls
800 E 21st St
Sioux Falls, SD 57105
(605)322-3500

Sioux Falls VA Medical Center
2501 W 22nd St
Sioux Falls, SD 57105
(605)336-3230

Children's Care Hospital & School
2501 W 26th St
Sioux Falls, SD 57105
(605)782-2300

Sanford USD Medical Center
1305 W 18th St
Sioux Falls, SD 57105
(605)333-1000

Heart Hospital of South Dakota
4500 W 69th St
Sioux Falls, SD 57108
(605)977-7000

Dells Area Health Center
909 N Iowa St
Dell Rapids, SD 57022
(605)428-5431

Canton-Inwood Memorial Hospital
440 N Hiawatha Dr
Canton, SD 57013
(605)987-2621

Sanford Hospital Luverne
1600 N Kniss Ave
Luverne, MN 56156
(507)283-2321

Merrill Pioneer Community Hospital
801 S Greene St
Rock Rapids, IA 51246
(712)472-2591

Pioneer Memorial Hospital
315 N Washington St
Viborg, SD 57070
(605)326-5161

Hegg Memorial Health Center
1202 21st Ave
Rock Valley, IA 51247
(712)476-8000

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