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Melanosis Coli Center - Savannah, GA

Savannah Gastroenterologist Doctors for Melanosis Coli

Type of Physician: Gastroenterologist

What is a Gastroenterologist?

A subspecialty certification by the Board of Internal Medicine; practitioners focus on the stomach, intestines, colon, liver, and gallbladder (digestive organs). The gastroenterologist treats conditions such as abdominal pain, ulcers, diarrhea, cancer, and jaundice and they consult with surgeons when abdominal operations are indicated.

Specialty: Gastroenterology

Common Name: GI Doctor

Gastroenterologist Doctors in Savannah *

Center for Digestive & Liver Health
Steven L Carpenter
1139 Lexington Ave
Savannah, GA 31404
(912) 303-4200

Center for Digestive & Liver Health
Charles W Duckworth
1139 Lexington Ave
Savannah, GA 31404
(912) 303-4200

Center for Digestive & Liver Health
Joseph M Hathaway
1139 Lexington Ave
Savannah, GA 31404
(912) 303-4200

Center for Digestive & Liver Health
Mark E Murphy
1139 Lexington Ave
Savannah, GA 31404
(912) 303-4200

Center for Digestive & Liver Health
Mark Nyce
1139 Lexington Ave
Savannah, GA 31404
(912) 303-4200

Center for Digestive & Liver Health
Edward Rydzak
1139 Lexington Ave
Savannah, GA 31404
(912) 303-4200

Center for Digestive & Liver Health
Ryan Wanamaker
1139 Lexington Ave
Savannah, GA 31404
(912) 303-4200

Jonathan C Glen MD
Jonathan C Glen
716 E 71st St
Savannah, GA 31405
(912) 355-1533

Gastroenterology Consultants
Gregory D Borak
519 Stephenson Ave
Savannah, GA 31405
(912) 354-9447

Gastroenterology Consultants
David M Chalikian
519 Stephenson Ave
Savannah, GA 31405
(912) 354-9447

Ronald R Fagin MD
Ronald R Fagin
613 Stevenson Ave
STE 203
Savannah, GA 31415
(912) 354-3954

Gastroenterology Consultants
Branden Hunter
519 Stephenson Ave
Savannah, GA 31405
(912) 354-9447

Gastroenterology Consultants
Frederick H Weber
519 Stephenson Ave
Savannah, GA 31405
(912) 354-9447

Gastroenterology Consultants
Michael Weinman
519 Stephenson Ave
Savannah, GA 31405
(912) 354-9447

Nicholas Costrini MD
Nicholas V Costrini
501 Eisenhower Dr
Savannah, GA 31406
(912) 354-2175

Statesboro Gastroenterology
Scot A Murray
1555 Brampton Ave
Statesboro, GA 30458
(912) 681-2007

East Georgia Gastroenterology Center
Rose L Cesar
1497 Fair Rd
STE 201
Statesboro, GA 30458
(912) 871-8500

Digestive Associates PC
Huitt E Mattox
3217 4th St
Brunswick, GA 31520
(912) 267-0058

Digestive Associates PC
Robin A Rittgers
3217 4th St
Brunswick, GA 31520
(912) 267-0058

Digestive Associates PC
Darrell E Schwertner
3217 4th St
Brunswick, GA 31520
(912) 267-0058

Digestive Associates PC
David Whitehead
3217 4th St
Brunswick, GA 31520
(912) 267-0058

Vantuil L Varges MD
Vantuil L Varges
96 B Lake Shore Dr
Saint Marys, GA 31558
(912) 882-2167

Savannah, Georgia

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Melanosis Coli

What is melanosis coli?

Melanosis coli is a condition usually associated with chronic laxative use in which dark pigment is deposited in the lamina propria (one of the lining layers) of the large intestine (colon). The pigment deposition results in a characteristic dark brown to black discoloration of the lining of the large intestine. This condition is sometimes called pseudomelanosis coli because the pigment deposits consist of a pigment known as lipofuscin and do not contain melanin as implied by the term "melanosis." Lipofuscin is a cellular pigment that forms when cells are destroyed, often called "wear and tear" pigment that can be found throughout the body.

The dark color of the intestinal lining may be uniform or patterned, and the discoloration may be slight or very pronounced. The intensity and pattern of the discoloration may even vary among different sites in the colon of a patient. The condition may also be reversed upon discontinuation of laxative use. In some cases, the wall of the colon appears normal to the eye, but microscopic evaluation of biopsies by a pathologist reveals areas of pigment in the colon's lining. The pigment in melanosis coli does not accumulate in polyps or tumors of the large intestine.

What are the symptoms of melanosis coli?

Melanosis coli does not cause symptoms.

What causes melanosis coli?

Melanosis coli usually results from chronic use of laxatives of the anthranoid group. Some examples of anthranoid laxatives are senna and rhubarb derivatives. Many of these laxatives have been in use for hundreds of years. In 1997, the U.S. Food and Drug Administration (FDA) banned the use of the popular anthranoid laxative phenolphthalein due to fears that it might be carcinogenic (cancer-causing). Animal studies had shown that extremely high doses of phenolphthalein led to tumors in animals, but it has nev...

Recommended Reading Related to Melanosis Coli

Constipation »

Constipation facts

  • Constipation is defined medically as fewer than three stools per week and severe constipation as less than one stool per week.
  • Constipation usually is caused by the slow movement of stool through the colon.
  • There are many causes of constipation including medications, poor bowel habits, low fiber diets, abuse of laxatives, hormonal disorders, and diseases primarily of other parts of the body that also affect the colon.
  • The two disorders limited to the colon that cause constipation are colonic inertia and pelvic floor dysfunction.
  • Medical evaluation for the cause of constipation should be done when constipation is of sudden onset, severe, worsening, associated with other worrisome symptoms such as loss of weight, or is not responding to simple, safe treatments.
  • Medical evaluation of constipation may include a history, physical examinatio...

Emergency Contact for Savannah

  • In case of Emergency, call 911

Nearby Savannah Hospitals *

Memorial Health University Medical Center
4700 Waters Ave
Savannah, GA 31404
(912)350-8000

Select Specialty Hosptial of Savannah
5353 Reynolds St
Savannah, GA 31405
(912)819-7972

St Joseph's Candler Health System
5353 Reynolds St
Savannah, GA 31405
(912)819-6000

Coastal Harbor Treatment Center
1150 Cornell Ave
Savannah, GA 31406
(912)354-3911

Georgia Regional Hospital at Savannah
1915 Eisenhower Dr
Savannah, GA 31406
(912)356-2011

St Joseph's Hospital
11705 Mercy Blvd
Savannah, GA 31419
(912)819-4100

Coastal Carolina Medical Center
1000 Medical Center Dr
Hardeeville, SC 29927
(843)784-8000

Hilton Head Regional Medical Center
25 Hospital Center Blvd
Hilton Head Island, SC 29926
(843)681-6122

Effingham Hospital
459 Highway 119 S
Springfield, GA 31329
(912)754-6451

Beaufort Memorial Hospital
955 Ribaut Rd
Beaufort, SC 29902
(843)522-5200

Liberty Regional Medical Center
462 E G Miles Pkwy
Hinesville, GA 31313
(912)369-9400

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