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Melanosis Coli Center - San Luis Obispo, CA

San Luis Obispo Gastroenterologist Doctors for Melanosis Coli

Type of Physician: Gastroenterologist

What is a Gastroenterologist?

A subspecialty certification by the Board of Internal Medicine; practitioners focus on the stomach, intestines, colon, liver, and gallbladder (digestive organs). The gastroenterologist treats conditions such as abdominal pain, ulcers, diarrhea, cancer, and jaundice and they consult with surgeons when abdominal operations are indicated.

Specialty: Gastroenterology

Common Name: GI Doctor

Gastroenterologist Doctors in San Luis Obispo *

Endoscopy Center of the Central Coast
Phillip M Colbert
77 Casa St
STE 108
San Luis Obispo, CA 93405
(805) 541-6080

Endoscopy Center of the Central Coast
Steven W Carlson
1551 Bishop St
STE 250
San Luis Obispo, CA 93401
(805) 543-8822

Endoscopy Center of the Central Coast
Gary L Cushing
1551 Bishop St
STE 250
San Luis Obispo, CA 93401
(805) 543-8822

Endoscopy Center of the Central Coast
Jeffrey B Mundorf
1551 Bishop St
STE 250
San Luis Obispo, CA 93401
(805) 543-8822

Endoscopy Center of the Central Coast
Vance D Rodgers
1551 Bishop St
STE 250
San Luis Obispo, CA 93401
(805) 543-8822

Stanford Liver Clinic
Aijaz Ahmed
1310 Las Tablas Rd
STE 204
Templeton, CA 93465
(805) 434-3458

Central Coast Gastroenterology
Jonathan L Riegler
1255 Las Tablas Rd
STE STE 201
Templeton, CA 93465
(805) 434-2434

Central Coast Gastroenterology
Paul D Wetzel
1255 Las Tablas Rd
STE STE 201
Templeton, CA 93465
(805) 434-2434

Central Coast Gastroenterology
Daniel C Zovich
1255 Las Tablas Rd
STE STE 201
Templeton, CA 93465
(805) 434-2434

Benipal & Feldman MDs
Paramjit Benipal
116 S Palisade Dr
STE 210
Santa Maria, CA 93454
(805) 347-7355

Bruce F Mize MD Inc
Paul Guarino
116 S Palisade Dr
STE 306
Santa Maria, CA 93454
(805) 614-9880

Atul B Vachhani MD
Thomas P Hsia
525 E Plaza Dr
STE 307
Santa Maria, CA 93454
(805) 922-6581

Bruce F Mize MD Inc
Bruce F Mize
116 S Palisade Dr
STE 306
Santa Maria, CA 93454
(805) 614-9880

Atul B Vachhani MD
Atul B Vachhani
525 E Plaza Dr
STE 307
Santa Maria, CA 93454
(805) 922-6581

GI Consultants
Thomas V Aguirre
2403 Castillo St
STE 201
Santa Barbara, CA 93105
(805) 682-3585

GI Consultants
Edward S Bentley
2403 Castillo St
STE 201
Santa Barbara, CA 93105
(805) 682-3585

Sansum Clinic
Vincent P Derosa
317 W Pueblo St
Gastroenterology Dept
Santa Barbara, CA 93105
(805) 898-3120

Sansum Clinic
James V Egan
317 W Pueblo St
Gastroenterology Dept
Santa Barbara, CA 93105
(805) 898-3120

Sansum Clinic
William V Hahn
317 W Pueblo St
Gastroenterology Dept
Santa Barbara, CA 93105
(805) 898-3120

Sansum Clinic
John D Hobson
317 W Pueblo St
Gastroenterology Dept
Santa Barbara, CA 93105
(805) 898-3120

Digestive Disease Consultants
William E Karnes
221 W Pueblo St
STE STE B
Santa Barbara, CA 93105
(805) 563-0024

Sansum Clinic
John L Petrini
317 W Pueblo St
Gastroenterology Dept
Santa Barbara, CA 93105
(805) 898-3120

Digestive Disease Consultants
Gary M VanDeventer
221 W Pueblo St
STE STE B
Santa Barbara, CA 93105
(805) 563-0024

Alvin Y Au MD
Alvin Y Au
1360 Bailey Dr
Hanford, CA 93230
(559) 584-6499

San Luis Obispo, California

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Melanosis Coli

What is melanosis coli?

Melanosis coli is a condition usually associated with chronic laxative use in which dark pigment is deposited in the lamina propria (one of the lining layers) of the large intestine (colon). The pigment deposition results in a characteristic dark brown to black discoloration of the lining of the large intestine. This condition is sometimes called pseudomelanosis coli because the pigment deposits consist of a pigment known as lipofuscin and do not contain melanin as implied by the term "melanosis." Lipofuscin is a cellular pigment that forms when cells are destroyed, often called "wear and tear" pigment that can be found throughout the body.

The dark color of the intestinal lining may be uniform or patterned, and the discoloration may be slight or very pronounced. The intensity and pattern of the discoloration may even vary among different sites in the colon of a patient. The condition may also be reversed upon discontinuation of laxative use. In some cases, the wall of the colon appears normal to the eye, but microscopic evaluation of biopsies by a pathologist reveals areas of pigment in the colon's lining. The pigment in melanosis coli does not accumulate in polyps or tumors of the large intestine.

What are the symptoms of melanosis coli?

Melanosis coli does not cause symptoms.

What causes melanosis coli?

Melanosis coli usually results from chronic use of laxatives of the anthranoid group. Some examples of anthranoid laxatives are senna and rhubarb derivatives. Many of these laxatives have been in use for hundreds of years. In 1997, the U.S. Food and Drug Administration (FDA) banned the use of the popular anthranoid laxative phenolphthalein due to fears that it might be carcinogenic (cancer-causing). Animal studies had shown that extremely high doses of phenolphthalein led to tumors in animals, but it has nev...

Recommended Reading Related to Melanosis Coli

Constipation »

Constipation facts

  • Constipation is defined medically as fewer than three stools per week and severe constipation as less than one stool per week.
  • Constipation usually is caused by the slow movement of stool through the colon.
  • There are many causes of constipation including medications, poor bowel habits, low fiber diets, abuse of laxatives, hormonal disorders, and diseases primarily of other parts of the body that also affect the colon.
  • The two disorders limited to the colon that cause constipation are colonic inertia and pelvic floor dysfunction.
  • Medical evaluation for the cause of constipation should be done when constipation is of sudden onset, severe, worsening, associated with other worrisome symptoms such as loss of weight, or is not responding to simple, safe treatments.
  • Medical evaluation of constipation may include a history, physical examinatio...

Emergency Contact for San Luis Obispo

  • In case of Emergency, call 911

Nearby San Luis Obispo Hospitals *

Sierra Vista Regional Medical Center
1010 Murray Ave
San Luis Obispo, CA 93405
(805)546-7600

French Hospital Medical Center
1911 Johnson Ave
San Luis Obispo, CA 93401
(805)543-5353

Atascadero State Hospital
10333 El Camino Real
Atascadero, CA 93422
(805)468-2000

Arroyo Grande Community Hospital
345 S Halcyon Rd
Arroyo Grande, CA 93420
(805)489-4261

Twin Cities Community Hospital
1100 Las Tablas Rd
Templeton, CA 93465
(805)434-3500

Marian Medical Center
1400 E Church St
Santa Maria, CA 93454
(805)739-3000

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