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Melanosis Coli Center - Odessa, TX

Odessa Gastroenterologist Doctors for Melanosis Coli

Type of Physician: Gastroenterologist

What is a Gastroenterologist?

A subspecialty certification by the Board of Internal Medicine; practitioners focus on the stomach, intestines, colon, liver, and gallbladder (digestive organs). The gastroenterologist treats conditions such as abdominal pain, ulcers, diarrhea, cancer, and jaundice and they consult with surgeons when abdominal operations are indicated.

Specialty: Gastroenterology

Common Name: GI Doctor

Gastroenterologist Doctors in Odessa *

Permain Gastroenterology Associates LLP
Ravikumar P Vemuru
315 E 5th St
Odessa, TX 79761
(432) 333-3433

Govind B Patel
Govind B Patel
4214 Andrews Hwy
STE 203
Midland, TX 79703
(432) 697-1000

Mrunal C Patel MD
Mrunal C Patel
4214 Andrews Hwy
STE 203
Midland, TX 79703
(432) 697-1000

Alma Ramos MD
Alma Ramos
1706 W Texas Ave
Midland, TX 79701
(432) 620-9797

Odessa, Texas

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Melanosis Coli

What is melanosis coli?

Melanosis coli is a condition usually associated with chronic laxative use in which dark pigment is deposited in the lamina propria (one of the lining layers) of the large intestine (colon). The pigment deposition results in a characteristic dark brown to black discoloration of the lining of the large intestine. This condition is sometimes called pseudomelanosis coli because the pigment deposits consist of a pigment known as lipofuscin and do not contain melanin as implied by the term "melanosis." Lipofuscin is a cellular pigment that forms when cells are destroyed, often called "wear and tear" pigment that can be found throughout the body.

The dark color of the intestinal lining may be uniform or patterned, and the discoloration may be slight or very pronounced. The intensity and pattern of the discoloration may even vary among different sites in the colon of a patient. The condition may also be reversed upon discontinuation of laxative use. In some cases, the wall of the colon appears normal to the eye, but microscopic evaluation of biopsies by a pathologist reveals areas of pigment in the colon's lining. The pigment in melanosis coli does not accumulate in polyps or tumors of the large intestine.

What are the symptoms of melanosis coli?

Melanosis coli does not cause symptoms.

What causes melanosis coli?

Melanosis coli usually results from chronic use of laxatives of the anthranoid group. Some examples of anthranoid laxatives are senna and rhubarb derivatives. Many of these laxatives have been in use for hundreds of years. In 1997, the U.S. Food and Drug Administration (FDA) banned the use of the popular anthranoid laxative phenolphthalein due to fears that it might be carcinogenic (cancer-causing). Animal studies had shown that extremely high doses of phenolphthalein led to tumors in animals, but it has nev...

Recommended Reading Related to Melanosis Coli

Constipation »

Constipation facts

  • Constipation is defined medically as fewer than three stools per week and severe constipation as less than one stool per week.
  • Constipation usually is caused by the slow movement of stool through the colon.
  • There are many causes of constipation including medications, poor bowel habits, low fiber diets, abuse of laxatives, hormonal disorders, and diseases primarily of other parts of the body that also affect the colon.
  • The two disorders limited to the colon that cause constipation are colonic inertia and pelvic floor dysfunction.
  • Medical evaluation for the cause of constipation should be done when constipation is of sudden onset, severe, worsening, associated with other worrisome symptoms such as loss of weight, or is not responding to simple, safe treatments.
  • Medical evaluation of constipation may include a history, physical examinatio...

Emergency Contact for Odessa

  • In case of Emergency, call 911

Nearby Odessa Hospitals *

Medical Center Hospital Odessa
500 W 4th St
Odessa, TX 79761
(432)640-4000

Regency Hospital of Odessa
500 W 4th St
Odessa, TX 79761
(432)552-4000

Odessa Regional Medical Center West Campus
520 E 6th St
Odessa, TX 79761
(432)582-8000

Odessa Regional Medical Center East Campus
515 N Adams Ave
Odessa, TX 79761
(432)582-8002

HEALTHSOUTH Midland Rehabilitation Hospital
1800 Heritage Blvd
Midland, TX 79707
(432)520-1600

Midland Memorial Hospital West Campus
4214 Andrews Hwy
Midland, TX 79703
(432)522-2273

Midland Memorial Hospital
2200 W Illinois Ave
Midland, TX 79701
(432)685-1111

Desert Springs Medical Center
3300 S FM 1788
Midland, TX 79706
(432)563-1200

Crane Memorial Hospital
1310 S Alford St
Crane, TX 79731
(432)558-3555

Martin County Hospital District
610 N St Peter St
Stanton, TX 79782
(432)756-3345

Ward Memorial Hospital
406 S Gary St
Monahans, TX 79756
(432)943-2511

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