megestrol, Megace, Megace ES (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

Blood clots in legs and lungs may occur.

Megestrol may worsen existing diabetes or lead to new onset diabetes.

PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

PREPARATIONS: Tablets: 20 and 40 mg. Oral suspension: 40 mg/mL or 125 mg/mL.

STORAGE: Megestrol should be stored in a dry place at room temperature, 15 C-25 C (59 F-77 F).

DOSING: The recommended dose for stimulating appetite is 800 mg per day of the regular megestrol suspension (40 mg/ml) or 625 mg per day of the ES formulation (125 mg/ml). Breast cancer is treated with 40 mg four times daily.

DRUG INTERACTIONS: Indinavir (Crixivan) reduces blood concentrations of megestrol. An increase in the dose of megestrol should be considered.

PREGNANCY: Megestrol may cause birth defects and should not be administered to pregnant women. Women should use contraception while taking megestrol.

NURSING MOTHERS: Megestrol should not be used while breastfeeding due to potential adverse effects in the infant.

Medically reviewed by Eni Williams, PharmD

Reference: FDA Prescribing Information


Medically Reviewed by a Doctor on 3/19/2015


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