megestrol, Megace, Megace ES

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GENERIC NAME: megestrol

BRAND NAME: Megace, Megace ES

DRUG CLASS AND MECHANISM: Megestrol is a synthetic female hormone belonging to the progesterone group. It is used for stimulating appetite and treating breast cancer. Progesterone is a hormone produced by the body, especially in women, that helps control the menstrual period as well as other body functions. How megestrol stimulates appetite or suppresses cancer is not understood. The FDA approved megestrol in September 1993.



PREPARATIONS: Tablets: 20 and 40 mg. Oral suspension: 40 mg/mL or 125 mg/mL.

STORAGE: Megestrol should be stored in a dry place at room temperature, 15-25 C (5977- F).

PRESCRIBED FOR: Megestrol is used for stimulating appetite in patients with acquired immunodeficiency syndrome (AIDS) who have poor appetite, cachexia, or an unexplained significant weight loss. It also is used for treating breast cancer and weight loss associated with cancer.

DOSING: The recommended dose for stimulating appetite is 800 mg per day of the regular megestrol suspension (40 mg/ml) or 625 mg per day of the ES formulation (125 mg/ml). Breast cancer is treated with 40 mg four times daily.

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