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mefloquine - oral, Lariam (cont.)

PRECAUTIONS: Before taking mefloquine, tell your doctor or pharmacist if you are allergic to it; or to quinine or quinidine; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.This medication should not be used if you have the following medical conditions: active or recent depression, anxiety disorder, psychiatric disorders, seizure disorders.Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart problems, liver problems.This medication may cause dizziness or loss of balance. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely.Use with caution in children.This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor.This drug passes into breast milk. Consult your doctor before breast-feeding.

DRUG INTERACTIONS: Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first.This drug should not be used with the following medications because very serious interactions may occur: artemether-lumefantrine, chloroquine, halofantrine, ketoconazole, quinidine, quinine, ziprasidone.Do not take halofantrine or ketoconazole for 15 weeks after your last dose of mefloquine.Tell your doctor of all prescription and nonprescription drugs you may use, especially of: beta-blockers (e.g., atenolol, propranolol), live bacterial vaccines, drugs for seizures (e.g., carbamazepine, phenytoin, valproic acid), drugs affecting liver enzymes that remove mefloquine from your body (such as rifamycins - including rifabutin and rifampin, and azole antifungals - including itraconazole and ketoconazole).This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.



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