medroxyprogesterone acetate (anticancer agent) - injection, Depo-Provera (cont.)
PRECAUTIONS: Before using medroxyprogesterone, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.This medication should not be used if you have any of the following conditions: history of stroke or other blood clots (e.g., in the legs, eyes, lungs), breast cancer, liver disease, current/suspected pregnancy, abnormal/unexplained vaginal bleeding.Before using this medication, tell your doctor or pharmacist your medical history, especially of: asthma, abnormal breast exam, family history of breast cancer, cancer of the reproductive organs (e.g., cervix), frequent use of alcohol/tobacco, depression, diabetes, heart disease (e.g., chest pain, heart failure), high blood pressure, kidney disease, migraine, personal/family history of bone disease (e.g., osteoporosis), seizures.Before having surgery, including dental surgery, tell your doctor or dentist that you are using this medication.This medication must not be used during pregnancy. If you become pregnant or think you may be pregnant, tell your doctor immediately.This drug passes into breast milk. Consult your doctor before breast-feeding.
DRUG INTERACTIONS: Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.This drug should not be used with the following medications because very serious interactions may occur: amprenavir, sodium tetradecyl sulfate.If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting medroxyprogesterone.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: acitretin, aminoglutethimide, anticonvulsants (e.g., phenytoin), corticosteroids (e.g., hydrocortisone, prednisone), isotretinoin, troleandomycin, warfarin.Certain drugs can decrease the amount of medroxyprogesterone in your system. These drugs include aprepitant, bexarotene, bosentan, dapsone, felbamate, griseofulvin, certain HIV protease inhibitors (e.g., indinavir, nelfinavir, ritonavir, zidovudine), nevirapine, modafinil, phenylbutazone, rifamycins (e.g., rifampin), many seizure medications (e.g., barbiturates, carbamazepine, topiramate), St. John's wort. Consult your doctor or pharmacist for details, and tell your doctor or pharmacist if you are taking any of the drugs listed above.This medication may interfere with certain laboratory tests (including certain hormone levels, thyroid tests), possibly causing false test results. Make sure laboratory personnel and all your doctors know you are using this medication.This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.
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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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