GENERIC NAME: MEDROXYPROGESTERONE - ORAL (meh-DROX-ee-pro-JESS-tur-own)
BRAND NAME(S): Amen, Cycrin, Progestone, Provera
Warning | Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage
WARNING: Two-drug combination hormone replacement therapy (estrogen and progestin menopause HRT) can infrequently cause cancer of the breast, heart disease (e.g., heart attack), stroke, dementia, and blood clots in the lung (pulmonary embolism) or leg. Estrogens may also increase the risk of cancer of the ovary. These risks appear to depend on the length of time this combination is used and the amount of estrogen per dose. Therefore, two-drug HRT should be used for the shortest possible length of time at the lowest effective dose, so you obtain the benefits and minimize the chance of serious side effects from long-term treatment. Discuss the risks and benefits with your doctor. If you use this drug for an extended period, you should be evaluated at least once a year. See Notes section. Blood clots may be more likely to form during very long periods of sitting or if you are bedridden, as well as with certain types of surgery. If this applies to you, ask your doctor whether you should temporarily stop your medication.
USES: This medication is a female hormone. It is used to treat amenorrhea (lack of menstrual flow), abnormal bleeding from the uterus, or endometriosis. It is also used to treat certain types of cancer, and menopausal symptoms as part of combination hormone replacement therapy (estrogen and progestin HRT). Progestins such as medroxyprogesterone lower the risk of estrogen-related cancer of the uterus during HRT therapy. Combination HRT should not be used to prevent heart disease.
HOW TO USE: May be taken with food or immediately after a meal to prevent stomach upset. Take this medication as prescribed. It is usually taken for 5 to 13 days during the later end of the menstrual cycle. A menstrual period should begin within 3 to 10 days of stopping the medication. For treatment of cancer, the medication is usually taken more often. Follow the dosing schedule carefully. Consult your doctor or pharmacist if you have any questions.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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