Medicines that Cause Depression (cont.)
How Can I Avoid Drugs That Cause Depression or Mania?
The best way to avoid
drugs that affect your mood is to know which medicines commonly cause depression
and/or mania. Then talk to your doctor to see if any of the medicines you are
taking are likely causing or contributing to mood symptoms, and if so, discuss
whether a different medication may be an appropriate option. Your doctor should
let you know up front which drugs might cause feelings of depression or mania
and should evaluate whether mood symptoms are or are not likely related to
Drugs That Might Cause Mania (Excessive Elation)
The following drugs could
cause symptoms of mania:
- Corticosteroids. This group of drugs decreases inflammation (swelling) and
reduces the activity of the immune system (cells that fight infection). Examples
include hydrocortisone, triamcinolone, prednisone, Flonase, Nasocort, Nasonex,
Flovent, and Azmacort.
- Cyclosporine. This drug is used to suppress the immune
system to prevent the rejection of transplanted organs.
- Dopar (levodopa). This
medicine treats Parkinson's disease.
- Lioresal. This is a muscle relaxant and
antispastic agent. It's often used to treat multiple sclerosis and spinal cord
- All antidepressants, including MAOIs (monoamine oxidase inhibitors,
such as Parnate or Nardil), SSRIs (selective serotonin reuptake inhibitors such
as Prozac, Lexapro and Paxil), SNRIs (serotonin/norepinephrine reuptake
inhibitors, such as Effexor, Pristiq and Cymbalta), and tricyclic
antidepressants (such Elavil or Pamelor).
- Ritalin or amphetamine. These are
stimulant drugs used to treat attention deficit hyperactivity disorder (ADHD).
- Synthroid. This drug is commonly prescribed as a thyroid hormone replacement.
- Trihexyphenidyl (Artane). This medicine is used to treat Parkinson's disease.
- Yohimbine. This drug treats male impotence.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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