- Rheumatoid Arthritis Slideshow Pictures
- Joint-Friendly Exercises to Reduce RA Pain Slideshow
- Take the RA Quiz
- What is meclofenamate, and how does it work (mechanism of action)?
- Is meclofenamate available as a generic drug?
- Do I need a prescription for meclofenamate?
- What are the uses for meclofenamate?
- What are the side effects of meclofenamate?
- What is the dosage for meclofenamate?
- Which drugs or supplements interact with meclofenamate?
- What else should I know about meclofenamate?
What is meclofenamate, and how does it work (mechanism of action)?
Meclofenamate belongs to a class of drugs called
Is meclofenamate available as a generic drug?
GENERIC AVAILABLE: Yes
Do I need a prescription for meclofenamate?
What are the uses for meclofenamate?
Meclofenamate is used for the relief of mild to moderate pain. It also is used to treat dysmenorrhea (painful periods), idiopathic heavy menstrual blood loss, and relief of the signs and symptoms of acute and chronic rheumatoid arthritis and osteoarthritis. Off label uses include ankylosing spondylitis (arthritis that mainly affects the spine) and vascular headache.
What are the side effects of meclofenamate?
The most common side effects are:
- abdominal pain with cramps,
- allergic reactions,
- heartburn, nausea, and
- skin rash.
It is important to note that people who take NSAIDs such as meclofenamate may have a higher risk of having a heart attack or a stroke than people who do not take these medications. Meclofenamate may cause ulcers, bleeding, or holes in the stomach or intestine. The risk may be higher for people who take NSAIDs for a longer period of time, are older in age, have poor health, or drink large amounts of alcohol.
If patients experience any of the following symptoms they should stop taking meclofenamate and call their doctor:
- stomach pain,
- vomiting a substance that is bloody or looks like coffee grounds,
- blood in the stool, or
- black and tarry stools.
- indomethacin (Indocin),
- naproxen (Naprosyn,
(Relafen) and several others. These drugs are used for the management of mild to moderate pain, fever, and inflammation. They work by reducing the levels of prostaglandins, chemicals that are responsible for pain, fever, and inflammation. Meclofenamate blocks the enzymes that make prostaglandins (cyclooxygenases), resulting in lower concentrations of prostaglandins. As a consequence, inflammation, pain, and fever are reduced. Meclofenamate was approved by the FDA in June 1980.
Quick GuideLyme Disease Symptoms, Rash, Treatments
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Need help identifying pills and medications?
Use the pill identifier tool on RxList.