meclizine, Antivert, Bonine, Meni-D, Antrizine (cont.)

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DOSING: When used for treating symptoms of motion sickness, meclizine 12.5-50 mg should be taken one hour prior to travel and then every 24 hours for the duration of the journey. The dosing should not exceed 50 mg  in 24 hours. Vertigo is treated with 25-100 mg daily in 4 divided dose

DRUG INTERACTIONS: Alcohol, sedatives, and tranquilizers can increase drowsiness caused by meclizine. Combining meclizine with pramlintide (Symlin) increases the effect of both drugs on slowing bowel movement.

PREGNANCY: Meclizine has been used to control nausea during pregnancy. Available evidence does not suggest that use of meclizine during pregnancy is harmful. However, meclizine should be used in pregnancy only if it is clearly needed and under the supervision of a physician.

NURSING MOTHERS: Available information suggests that the risk of harm to the baby is minimal when meclizine is used while breastfeeding.

SIDE EFFECTS: Meclizine can cause drowsiness. Other side effects include nausea, dry mouth, blurred vision, rash constipation, diarrhea and urinary retention (inability or difficulty urinating). Meclizine also has been associated with hypotension (low blood pressure) and heart palpitations.

Reference: FDA Prescribing Information

Medically Reviewed by a Doctor on 7/31/2014

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