GENERIC NAME: meclizine
DISCONTINUED BRANDS: Antivert, Bonine, Meni-D, Antrizine
DRUG CLASS AND MECHANISM: Meclizine is an antihistamine with antiemetic (anti-nausea) and antispasmodic (anti-muscle spasm) activity. It also suppresses the nervous system by blocking the action of the neurotransmitter acetylcholine. (Neurotransmitters are chemicals that nerves use for communicating with each other.) Meclizine prevents nausea and vomiting by reducing the activity of the center in the brain that controls nausea. It also prevents motion sickness by reducing excitability of neurons in the motion and balance center (vestibular region) of the brain. The FDA approved meclizine in February 1957.
PRESCRIBED FOR: Meclizine is used for the treatment of nausea, vomiting, and dizziness associated with motion sickness. Meclizine possibly is effective in the treatment of vertigo (balance disorder) caused by diseases of the body's balance (vestibular) system.
SIDE EFFECTS: Meclizine can cause drowsiness. Other side effects include:
- dry mouth,
- blurred vision,
- diarrhea and
- urinary retention (inability or difficulty urinating).
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