Measles (Rubeola) (cont.)

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What adverse reactions can occur with the measles vaccination?

Adverse reactions to measles vaccination (as part of the MMR) include fever (5%-15%), rash (5%), joint aches (5%), and low platelet count (thrombocytopenia; one instance per 30,000 doses). In adult women, up to 25% will suffer joint pain that is due to the rubella component of the vaccine. The fever usually occurs seven to 12 days after the vaccination, and the rash occurs seven to 10 days after vaccination.

Who should be revaccinated against measles?

The following group of people should be considered unvaccinated and should receive at least one dose of vaccine:

  • People vaccinated before their first birthday should be revaccinated.
  • Anyone known to have been vaccinated with the killed measles vaccine (KMV) should be revaccinated.
  • Anyone vaccinated with KMV who received their dose of live measles vaccine with four months of their last dose of vaccine should be revaccinated.
  • Anyone vaccinated before 1968 in whom it is not known if the vaccine was KMV or not should be revaccinated.

Where can I find more information about measles?

"Measles (Rubeola)," U.S. Centers for Disease Control and Prevention

Chapter 7: "Measles," VPD Surveillance Manual

"Measles," World Health Organization

"WHO Vaccine-Preventable Diseases: Monitoring System," World Health Organization

Handouts: Clinic Resources, Immunization Action Coalition

REFERENCES:

American Academy of Pediatrics. "Measles." Red Book: 2006 Report of the Committee on Infectious Diseases, 28th ed. Ed. Pickering, L.K. Elk Grove Village, IL: American Academy of Pediatrics, 2006.

Perry, R.T., and N.A. Halsey. "The Clinical Significance of Measles: A review." J Infect Dis 189 (2004): S4–16.

United States. Centers for Disease Control and Prevention. "Measles." Manual for the Surveillance of Vaccine-Preventable Diseases, 4th ed. 2008. <http://www.cdc.gov/vaccines/pubs/surv-manual/chpt07-measles.htm>.

United States. Centers for Disease Control and Prevention. "Measles, Mumps, and Rubella -- Vaccine Use and Strategies for Elimination of Measles, Rubella, and Congenital Rubella Syndrome and Control of Mumps: Recommendations of the Advisory Committee on Immunization Practices (ACIP)." MMWR 47 (No. RR-8) 1998: 1–57.

United States. Centers for Disease Control and Prevention. "Notes from the Field: Measles Transmission Associated With International Air Travel -- Massachusetts and New York, July -- August 2010." MMWR 59.33 Aug. 2010: 1073.

United States. Centers for Disease Control and Prevention. "Use of Combination Measles, Mumps, Rubella, and Varicella Vaccine: Recommendations of the Advisory Committee on Immunization Practices (ACIP)." MMWR 59(RR03) 2010: 1-12.

World Health Organization. "Fifty-Sixth World Health Assembly. Agenda item 14.7. Reducing Global Measles Mortality." Geneva: World Health Organization, 2003. <http://www.who.int/gb/ebwha/pdf_files/WHA56/
ea56r20.pdf>.


Last Editorial Review: 6/20/2012


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