MMR Vaccine (measles, mumps, and rubella virus vaccine, live)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

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DOSING:

Children should get 2 injections of the measles, mumps, and rubella vaccine under the skin (subcutaneously):

  • First injection (0.5 ml) at 12-15 months of age
  • Second injection (0.5 ml) at 4-6 years age

Some adults also may need the measles, mumps, and rubella vaccine. It is generally recommended that adults who were born in 1957 or later should get at least one injection of the measles, mumps, and rubella vaccine. However, the vaccine is not needed in people who have laboratory evidence of immunity (antibodies) to the three viruses.

DRUG INTERACTIONS:

Anyone who has ever had a life-threatening allergic reaction to the antibiotic neomycin should not get the measles, mumps, and rubella vaccine.

Patients who are sick should get the vaccine at a later time after they have recovered.

Patients with a weak immune system may not fully benefit from the measles, mumps, and rubella vaccine.

Some medications may decrease the effectiveness of the measles, mumps, and rubella vaccine. Examples include fingolimod (Gilenya), belimumab (Benlysta), anakinra (Kineret), adalimumab (Humira), infliximab (Remicade), antineoplastic agents (anti-cancer medications), and other medicines that decrease the immune response.

The measles, mumps, and rubella vaccine may interact with the tuberculin (TB) test. The TB skin test should not be performed in patients who have received the measles, mumps, and rubella vaccine within the previous 4-6 weeks.

PREGNANCY: Pregnant women should not get the measles, mumps, and rubella vaccine. Pregnant women who need the vaccine should wait until after giving birth to get the vaccine. Additionally, females who have received the vaccine should avoid getting pregnant for 4 weeks (28 days) after vaccination.

NURSING MOTHERS: It is not known if the measles or mumps vaccine can enter human milk. The rubella vaccine however may be excreted into human milk but usually does not cause side effects in the nursing baby.

REFERENCE: FDA Prescribing Information

Medically Reviewed by a Doctor on 9/24/2015

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