Marijuana

Are there any interactions with medications?

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Sedative medications (Barbiturates)
Interaction Rating: Major Do not take this combination.

Marijuana might cause sleepiness and drowsiness. Medications that cause sleepiness are called sedatives. Taking marijuana along with sedative medications might cause too much sleepiness.

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Sedative medications (CNS depressants)
Interaction Rating: Major Do not take this combination.

Marijuana might cause sleepiness and drowsiness. Medications that cause sleepiness are called sedatives. Taking marijuana along with sedative medications might cause too much sleepiness.

Some sedative medications include clonazepam (Klonopin), lorazepam (Ativan), phenobarbital (Donnatal), zolpidem (Ambien), and others.

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Theophylline
Interaction Rating: Major Do not take this combination.

Taking marijuana might decrease the effects of theophylline. But there isn't enough information to know if this is a big concern.

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Disulfiram (Antabuse)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Disulfiram (Antabuse) might interact with marijuana. Taking marijuana along with Disulfiram can cause agitation, trouble sleeping, and irritability.

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Fluoxetine (Prozac)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Taking marijuana with fluoxetine (Prozac) might cause you to feel irritated, nervous, jittery, and excited. Doctors call this hypomania.

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Warfarin (Coumadin)
Interaction Rating: Minor Be cautious with this combination.
Talk with your health provider.

Using marijuana might increase the effects of warfarin (Coumadin). Smoking marijuana while taking warfarin (Coumadin) might increase the chance of bruising and bleeding.

Dosing considerations for Marijuana.

The following doses have been studied in scientific research:

BY MOUTH:

• The prescription product dronabinol (Marinol), which is one chemical in marijuana, is used in doses of 5 to 15 mg/m2 every 2 for 4 hours for nausea and vomiting due to cancer chemotherapy, and 2.5 to 10 mg twice daily for improving appetite in people with AIDS. However, current scientific information indicates that smoking or inhaling marijuna might not be safe. Talk with your healthcare provider before using this product.