mao inhibitors-oral (cont.)
DRUG INTERACTIONS: This drug should not be used with the following medications because very serious interactions may occur: apraclonidine, brimonidine, bethanidine, bupropion, buspirone, carbamazepine, dextromethorphan, entacapone, herbal products (e.g., ma huang), indoramin, meperidine, papaverine, sibutramine, SSRI antidepressants (e.g., fluoxetine, citalopram), sympathomimetics (e.g., methylphenidate, ephedrine), tolcapone, tricyclic antidepressants (e.g., amitriptyline, doxepin), "triptans" (e.g., sumatriptan, zolmitriptan). If you are currently using any of these medications, tell your doctor or pharmacist before starting a MAO inhibitor. Before using this medication, be sure to tell your doctor what medicines (both prescription and nonprescription) you are taking, including: levodopa, tryptophan, insulin and oral antidiabetic drugs, other MAO inhibitors (e.g., furazolidone, linezolid, moclobemide, selegiline), sedatives and drugs used to aid sleep, blood pressure medications. Consult your doctor about the need to watch your intake of foods containing tyramine. It is possible consuming tyramine- containing foods while using this medication could cause headache and/or increased blood pressure and could lead to a medical emergency. Tyramine food precautions should be observed for at least 2 weeks after you stop using this medication. The following is a partial list of tyramine-containing foods: Meat or Fish - pickled herring/liver/dry sausage/salami/meats prepared with tenderizer; Dairy - yogurt/sour cream/aged cheeses (cream or cottage cheese are okay); Beverages - beer/red wine/sherry - Avoid excessive amount of caffeine-containing colas/coffee/tea; Fruits and Vegetables - avocado/bananas/figs/raisins/broad beans/sauerkraut; Other - yeast extract/soy sauce/large amounts of chocolate. Do not start or stop any medicine without doctor or pharmacist approval.
OVERDOSE: If overdose is suspected, contact your local poison control center at 1-800-222-1222 (USA) or emergency room immediately. Symptoms of overdose may include convulsions, cool or clammy skin, severe dizziness or headache, hallucinations, drowsiness, slow or shallow breathing, fainting, irritability, sleeplessness, anxiety, weakness, sweating, confusion, unconsciousness, unusual fast heartbeat, or chest pain.
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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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