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- What is mannitol-injectable, and how does it work (mechanism of action)?
- What brand names are available for mannitol-injectable?
- Is mannitol-injectable available as a generic drug?
- Do I need a prescription for mannitol-injectable?
- What are the side effects of mannitol-injectable?
- What is the dosage for mannitol-injectable?
- Which drugs or supplements interact with mannitol-injectable?
- Is mannitol-injectable safe to take if I'm pregnant or breastfeeding?
- What else should I know about mannitol-injectable?
What is the dosage for mannitol-injectable?
- Prevention of acute renal railure (oliguria): 50 to100 g of mannitol given as 5%, 10%, or 15% solution depending on the patient's fluid requirements.
- Treatment of oliguria: 100 g administered as a 15 or 20% solution.
- Reduction of intracranial pressure and brain mass: 0.25 g/kg given every 6 to 8 hours.
- Reduction of intraocular pressure: 1.5 to 2 g/kg body weight, as 15% to 25% solution administered over 30 to 60 minutes.
- Adjunctive therapy for intoxications: Adults may receive a 5% to 25% solution for as long as urinary output remains high.
Which drugs or supplements interact with mannitol-injectable?
Mannitol should not be used with tobramycin, because mannitol increases tobramycin levels significantly through an unknown mechanism.
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