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February 10, 2012
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mannitol-injectable, Osmitrol

GENERIC NAME: MANNITOL - INJECTABLE (MAN-ih-tole)

BRAND NAME(S): Osmitrol

Medication Uses | Other Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage

USES: Mannitol is used to increase urine production (diuretic). It is used to treat or prevent medical conditions that are caused by an increase in body fluids/water (e.g., cerebral edema, glaucoma, kidney failure). This medication is frequently given along with other diuretics (e.g., furosemide, chlorothiazide) and/or IV fluid replacement.

OTHER USES: This drug may also be used, along with other diuretics, to help remove certain drugs/poisons from the body (e.g., aspirin, barbiturates, bromides, carbon monoxide)

HOW TO USE: A small test dose of this medication may be given as directed by your doctor. This small test dose should help determine your response to treatment. Give this medication by vein (IV) exactly as directed by your doctor. The dosage is based on your weight, medical condition, and response to treatment. This medication may contain small particles in the IV solution. It is very important to use an IV filter while giving this solution. Consult your pharmacist for the proper IV filter and its instructions for use. Under certain conditions (e.g., cool temperatures), crystals may form in this medication. Although these crystals do not affect the medication solution, the crystals must be dissolved before using this product. Consult your pharmacist for more information. Before using check this product for particles or discoloration. If either is present do not use the liquid. Learn how to store and discard needles and medical supplies safely. Consult your pharmacist.

SIDE EFFECTS: Headache, nausea, diarrhea, vomiting, dry mouth, and irritation/pain/swelling at the injection site may occur. If any of these effects persist or worsen, notify your doctor promptly. Tell your doctor immediately if any of these serious side effects occur: blurred vision, change in amount of urine, back pain. Tell your doctor immediately if any of these unlikely but serious side effects occur: mental/mood changes, trouble breathing, slow or shallow breathing, unusual swelling. Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: uncontrolled muscle movements (tremor), seizures, chest pain, black/dead-looking skin (necrosis). An allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.




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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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mannitol-injectable, Osmitrol

What is glaucoma?

Glaucoma is a disease of the major nerve of vision, called the optic nerve. The optic nerve receives light-generated nerve impulses from the retina and transmits these to the brain, where we recognize those electrical signals as vision. Glaucoma is characterized by a particular pattern of progressive damage to the optic nerve that generally begins with a subtle loss of side vision (peripheral vision). If glaucoma is not diagnosed and treated, it can progress to loss of central vision and blindness.

Glaucoma is usually, but not always, associated with elevated pressure in the eye (intraocular pressure). Generally, it is this elevated eye pressure that leads to damage of the eye (optic) nerve. In some cases, glaucoma may occur in the presence of normal eye pressure. This form of glaucoma is believed to be caused by poor regulation of blood flow to the optic nerve.

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