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GENERIC NAME: MANNITOL - INJECTABLE (MAN-ih-tole)

BRAND NAME(S): Osmitrol

Medication Uses | Other Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage

USES: Mannitol is used to increase urine production (diuretic). It is used to treat or prevent medical conditions that are caused by an increase in body fluids/water (e.g., cerebral edema, glaucoma, kidney failure). This medication is frequently given along with other diuretics (e.g., furosemide, chlorothiazide) and/or IV fluid replacement.

OTHER USES: This drug may also be used, along with other diuretics, to help remove certain drugs/poisons from the body (e.g., aspirin, barbiturates, bromides, carbon monoxide)

HOW TO USE: A small test dose of this medication may be given as directed by your doctor. This small test dose should help determine your response to treatment. Give this medication by vein (IV) exactly as directed by your doctor. The dosage is based on your weight, medical condition, and response to treatment. This medication may contain small particles in the IV solution. It is very important to use an IV filter while giving this solution. Consult your pharmacist for the proper IV filter and its instructions for use. Under certain conditions (e.g., cool temperatures), crystals may form in this medication. Although these crystals do not affect the medication solution, the crystals must be dissolved before using this product. Consult your pharmacist for more information. Before using check this product for particles or discoloration. If either is present do not use the liquid. Learn how to store and discard needles and medical supplies safely. Consult your pharmacist.

SIDE EFFECTS: Headache, nausea, diarrhea, vomiting, dry mouth, and irritation/pain/swelling at the injection site may occur. If any of these effects persist or worsen, notify your doctor promptly. Tell your doctor immediately if any of these serious side effects occur: blurred vision, change in amount of urine, back pain. Tell your doctor immediately if any of these unlikely but serious side effects occur: mental/mood changes, trouble breathing, slow or shallow breathing, unusual swelling. Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: uncontrolled muscle movements (tremor), seizures, chest pain, black/dead-looking skin (necrosis). An allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.




Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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mannitol-injectable, Osmitrol

What is edema?

Edema is observable swelling from fluid accumulation in body tissues. Edema most commonly occurs in the feet and legs, where it is referred to as peripheral edema. The swelling is the result of the accumulation of excess fluid under the skin in the spaces within the tissues. All tissues of the body are made up of cells and connective tissues that hold the cells together. This connective tissue around the cells and blood vessels is known as the interstitium. Most of the body's fluids that are found outside of the cells are normally stored in two spaces; the blood vessels (as the "liquid" or serum portion of your blood) and the interstitial spaces (not within the cells). In various diseases, excess fluid can accumulate in either one or both of these compartments.

The body's organs have interstitial spaces where fluid can accumulate. An accumulation of fluid in the interstitial air spaces (alveoli) in the lungs occurs in a disorder called...

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