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In this Article

• Malignant hyperthermia facts*
• What is malignant hyperthermia?
• How common is malignant hyperthermia?
• What genes are related to malignant hyperthermia?
• How do people inherit malignant hyperthermia?
• Where can I find information about diagnosis, management, or treatment of malignant hyperthermia?
• What other names do people use for malignant hyperthermia?
• Find a local Doctor in your town
• Malignant Hyperthermia Index

Malignant hyperthermia susceptibility is inherited in an autosomal dominant pattern, which means one copy of the altered gene in each cell is sufficient to increase the risk of a severe reaction to certain drugs used during surgery. In most cases, an affected person inherits the altered gene from a parent who is also at risk for the condition.

These resources address the diagnosis or management of malignant hyperthermia and may include treatment providers.

• Gene Review: Malignant Hyperthermia Susceptibility.
• Gene Tests: CACNA1S-Related Malignant Hyperthermia Susceptibility.
• Gene Tests: MHS2-Related Malignant Hyperthermia Susceptibility.
• Gene Tests: MHS3-Related Malignant Hyperthermia Susceptibility.
• Gene Tests: MHS4-Related Malignant Hyperthermia Susceptibility.
• Gene Tests: RYR1-Related Malignant Hyperthermia Susceptibility.

To locate a healthcare provider, see How can I find a genetics professional in my area? in the Handbook. Where can I find additional information about malignant hyperthermia?

• anesthesia related hyperthermia
• Hyperpyrexia, Malignant
• Hyperthermia, Malignant
• Malignant Hyperpyrexia
• MHS - Malignant hyperthermia

SOURCE: Genetics Home Reference. Malignant hyperthermia.