malathion (Ovide) (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

Malathion is flammable

PREPARATIONS:

  • Lotion: 0.5%

DRUG INTERACTIONS:

PREGNANCY AND BREASTFEEDING SAFETY:

  • Malathion has not been adequately evaluated in pregnant women. Available data from animals suggests that the risk of fetal toxicity is low. It should be used (or handled) during pregnancy only if clearly needed.
  • It is not known whether malathion is excreted in breast milk.

STORAGE:

  • Malathion should be stored at room temperature, 20 C - 25 C (68 F - 77 F). It is flammable and should be kept away from heat and open flame.

DOSING:

  1. Dry hair and scalp should be thoroughly wet with malathion lotion, including the back of the head and neck. The hands should be washed after applying.
  2. The hair should not be covered and should dry naturally without using an electric heat source.
  3. The hair should be shampooed after 8 to 12 hours, rinsed and combed with a fine - toothed (nit) comb to remove dead lice and eggs.
  4. Malathion lotion should be applied again if lice are still present after 7 - 9 days.

DRUG CLASS AND MECHANISM:

  • Malathion is a pesticide used for killing head lice (Pediculus humanus capitis). It kills head lice and lice eggs by blocking the activity of enzymes (cholinesterase) that breaks-down and inactivates acetylcholine (a neurotransmitter) in head lice. This causes high levels of acetylcholine which leads to death of lice.
  • The FDA approved malathion in August, 1982.

REFERENCE: FDA Prescribing Information


Medically Reviewed by a Doctor on 4/6/2016


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