GENERIC NAME: magnesium sulfate
BRAND NAME: Chloromag
DRUG CLASS AND MECHANISM: Magnesium sulfate is a sterile solution of magnesium sulfate heptahydrate in water for injection. Magnesium sulfate prevents convulsions by blocking transmission between nerves and muscles. It also reduces the amount of t acetylcholine, a chemical that nerves use for communicating with other nerves and tissues.
SIDE EFFECTS: Side effects of magnesium sulfate are:
- (low blood pressure),
- lowered body temperature,
- cardiac and central nervous system depression.
GENERIC AVAILABLE: Yes
PREPARATIONS: Intramuscular magnesium sulfate available in 500 mg/ml strength, in 2 ml, 10 ml, and 50 ml single-use vials.
Intravenous magnesium sulfate is available in 40mg/ml and 80mg/ml strengths. 40 mg/ml concentration is available in 50 ml, 100 ml, 500 ml, and 1000 ml single-dose, plastic containers. 80 mg/ml concentration is available in 50 ml partial-fill, single-dose, flexible plastic container.
STORAGE: Intramuscular magnesium sulfate injections are stored between 15 C to 30 C (59 F to 86 F). Intravenous magnesium sulfate injections are stored between 20 C to 25 C (68 F to 77 F).
- Mild: Inject 1 gram intramuscularly (IM) every 6 hours for 4 doses.
- Severe: 5 grams administered intravenously (IV) over 3 hours.
- Maintenance: 30-60 mg/kg/day IV.
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