Macular Degeneration (Age-Related Type) Glossary of Terms

Abnormal: Not normal. Deviating from the usual structure, position, condition, or behavior. In referring to a growth, abnormal may mean that it is cancerous or premalignant (likely to become cancer ).
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Age-related macular degeneration : An eye disease with its onset usually after age 60 that progressively destroys the macula , the central portion of the retina , impairing central vision . Age-related macular degeneration (AMD) rarely causes blindness because only the center of vision is affected. However, injury to the macula in the center of the retina can impair the ability to see straight ahead clearly and sometimes make it difficult to read, drive, or perform other daily activities that require fine central vision.
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Aging: The process of becoming older, a process that is genetically determined and environmentally modulated.
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Amsler grid: While conducting an eye examination, the eye care professional may ask the patient to look at an Amsler grid. This grid is a pattern that resembles a checkerboard. The patient covers one eye and stares at a black dot in the center of the grid. While staring at the dot, the patient may notice that the straight lines in the pattern appear wavy.

Anemia: The condition of having less than the normal number of red blood cells or less than the normal quantity of hemoglobin in the blood. The oxygen-carrying capacity of the blood is, therefore, decreased.
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Angiogram: An x-ray of blood vessels which can be seen because the patient receives an injection of dye to outline the vessels on the x-ray.

Arm: 1. In popular usage, the appendage that extends from the shoulder to the hand. However, the medical definition refers to the upper extremity extending from the shoulder only to the elbow, excluding the forearm, which extends from the elbow to the wrist. The arm contains one bone: the humerus. 2. In a randomized clinical trial, any of the treatment groups. Most randomized trials have two "arms," but some have three "arms," or even more.

Blind: 1. Unable to see. Without part or all of the sense of sight.
2. In a clinical trial, not to know the treatment given or received. The participant is not told whether they are in the experimental or control arm of the study. Also called masked.
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Blind spot: In ophthalmology, a blind spot is:

1. A small area of the retina where the optic nerve enters the eye; this type of blind spot occurs normally in all eyes.
2. Any gap in the visual field corresponding to an area of the retina where no visual cells are present; this type of blind spot is associated with eye disease.

Blood: The familiar red fluid in the body that contains white and red blood cells, platelets, proteins, and other elements. The blood is transported throughout the body by the circulatory system. Blood functions in two directions: arterial and venous. Arterial blood is the means by which oxygen and nutrients are transported to tissues while venous blood is the means by which carbon dioxide and metabolic by-products are transported to the lungs and kidneys, respectively, for removal from the body.

Blood pressure: The blood pressure is the pressure of the blood within the arteries. It is produced primarily by the contraction of the heart muscle. It's measurement is recorded by two numbers. The first (systolic pressure) is measured after the heart contracts and is highest. The second (diastolic pressure) is measured before the heart contracts and lowest. A blood pressure cuff is used to measure the pressure. Elevation of blood pressure is called "hypertension".

Blurred vision: Lack of sharpness of vision with, as a result, the inability to see fine detail. Blurred vision can occur when a person who wears corrective lens is without them. Blurred vision can also be an important clue to eye disease.

Brain: That part of the central nervous system that is located within the cranium ( skull ). The brain functions as the primary receiver, organizer and distributor of information for the body. It has two (right and left) halves called "hemispheres."
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Central vision: Straight-ahead vision. Central vision is the work of the macula, a small area in the center of the retina that contains a rich collection of cones. (The retina is made up of two types of cells, the cones and the rods. Millions of cones are packed into the macula. The cones are nerve cells sensitive to light, fine detail, and color.) Central vision permits a person to read, drive, and perform other activities that require fine, sharp, straight-ahead vision. As opposed to peripheral vision.

Condition: The term "condition" has a number of biomedical meanings including the following:

1. An unhealthy state, such as in "this is a progressive condition."
2. A state of fitness, such as "getting into condition."
3. Something that is essential to the occurrence of something else; essentially a "precondition."
4. As a verb: to cause a change in something so that a response that was previously associated with a certain stimulus becomes associated with another stimulus; to condition a person, as in behavioral conditioning.

Cure: 1. To heal, to make well, to restore to good health. Cures are easy to claim and, all too often, difficult to confirm.
2. A time without recurrence of a disease so that the risk of recurrence is small, as in the 5-year cure rate for malignant melanoma .
3. Particularly in the past, a course of treatment. For example, take a cure at a spa.
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Diagnosis: 1 The nature of a disease ; the identification of an illness. 2 A conclusion or decision reached by diagnosis. The diagnosis is rabies . 3 The identification of any problem. The diagnosis was a plugged IV.
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Dilate: To stretch or enlarge. It comes from the Latin verb "dilatare" meaning "to enlarge or expand."

Dilating: The widening and opening of the cervix caused by uterine contractions.

Drusen: Tiny yellow or white deposits in the retina of the eye or on the optic nerve head.
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Eye chart test: This test measures how well you see at various distances. The eye chart itself -- the usual one is called Snellen's chart -- is imprinted with block letters that line-by-line decrease in size, corresponding to the distance at which that line of letters is normally visible.
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Family history: The family structure and relationships within the family, including information about diseases in family members.
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Fovea: In the eye, a tiny pit located in the macula of the retina that provides the clearest vision of all. Only in the fovea are the layers of the retina spread aside to let light fall directly on the cones, the cells that give the sharpest image. Also called the central fovea or fovea centralis.
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Genetic: Having to do with genes and genetic information.

Laser: A powerful beam of light that can produce intense heat when focused at close range. Lasers are used in medicine in microsurgery, cauterization, for diagnostic purposes, etc. For example, lasers are employed in microsurgery to cut tissue and remove tissue.
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Laser surgery: A type of surgery that uses the cutting power of a laser beam to make bloodless cuts in tissue or remove a surface lesion such as a skin tumor. There are a number of different types of lasers that differ in emitted light wavelengths and power ranges and in their ability to clot, cut, or vaporize tissue. Among the commonly used lasers are the pulsed-dye laser, the YAG laser, the CO2 (carbon dioxide) laser, the argon laser, the excimer laser, the KTP laser, and the diode laser.

Lens: The transparent structure inside the eye that focuses light rays onto the retina (the nerve layer that lines the back of the eye, senses light and creates impulses that go through the optic nerve to the brain). The lens was named after the lentil bean because it resembled it in shape and size.
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Low vision: A visual impairment, not corrected by standard glasses, contact lenses, medicine, or surgery, that interferes with the ability to perform everyday activities. Most people develop low vision because of eye diseases such as cataracts , glaucoma , diabetic retinopathy or age-related macular degeneration (AME). Low vision primarily affects people over age 65. High risk populations include Hispanics and African Americans, who are likely to develop low vision at an earlier age. While lost vision usually cannot be restored, many people can learn to make the most of the vision that remains.
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Macula: A macula is a small spot. A macula on the skin is a small flat spot while the macula in the eye is a small spot where vision is keenest in the retina.

Macular: Pertaining to the macula. A macula is a small spot. A macula on the skin is a small flat spot while the macula in the eye is a small spot where vision is keenest in the retina .

Macular degeneration : A disease that progressively destroys the macula , the central portion of the retina , impairing central vision . Macular degeneration rarely causes blindness because only the center of vision is affected. However, injury to the macula in the center of the retina can impair the ability to see straight ahead clearly and sometimes make it difficult to read, drive, or perform other daily activities that require fine central vision.
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Nerve: A bundle of fibers that uses chemical and electrical signals to transmit sensory and motor information from one body part to another. See: Nervous system.

Obesity: The state of being well above one's normal weight.
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Onset: In medicine, the first appearance of the signs or symptoms of an illness as, for example, the onset of rheumatoid arthritis . There is always an onset to a disease but never to the return to good health. The default setting is good health.
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Optic: Having to do with vision.

Optic nerve: The optic nerve connects the eye to the brain. The optic nerve carries the impulses formed by the retina, the nerve layer that lines the back of the eye and senses light and creates impulses. These impulses are dispatched through the optic nerve to the brain, which interprets them as images. Using an ophthalmoscope, the head of the optic nerve can be easily seen. It can be viewed as the only visible part of the brain (or extension of it).
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Osteoporosis: Thinning of the bones with reduction in bone mass due to depletion of calcium and bone protein . Osteoporosis predisposes a person to fractures, which are often slow to heal and heal poorly. It is more common in older adults, particularly post-menopausal women; in patients on steroids; and in those who take steroidal drugs. Unchecked osteoporosis can lead to changes in posture , physical abnormality (particularly the form of hunched back known colloquially as " dowager's hump "), and decreased mobility.
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Pain: An unpleasant sensation that can range from mild, localized discomfort to agony. Pain has both physical and emotional components. The physical part of pain results from nerve stimulation. Pain may be contained to a discrete area, as in an injury, or it can be more diffuse, as in disorders like fibromyalgia . Pain is mediated by specific nerve fibers that carry the pain impulses to the brain where their conscious appreciation may be modified by many factors.
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Photodynamic therapy: A form of cancer treatment using an photosensitizing agent administered intravenously which concentrates selectively in tumor cells, followed by exposure of the tumor tissue to a special red laser light, in order to destroy as much of the tumor as possible.
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Recurrence: The return of a sign, symptom or disease after a remission. The reappearance of cancer cells at the same site or in another location is, unfortunately, a familiar form of recurrence.
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Referral: The recommendation of a medical or paramedical professional. If you get a referral to ophthalmology, for example, you are being sent to the eye doctor. In HMOs and other managed care schemes, a referral is usually necessary to see any practitioner or specialist other than your primary care physician (PCP), if you want the service to be covered. The referral is obtained from your PCP, who may require a telephone or office consultation first.
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Retina: The retina is the nerve layer that lines the back of the eye, senses light, and creates impulses that travel through the optic nerve to the brain. There is a small area, called the macula, in the retina that contains special light-sensitive cells. The macula allows us to see fine details clearly.
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Retinal: Pertaining to the retina , the extraordinary layer of neurons (nerve cells) that line the back of the eye, which can sense light and create impulses capable of voyaging through the optic nerve to the brain where the impulses are recognized as an image.
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Risk factor: Something that increases a person's chances of developing a disease.

Risk of recurrence: In medical genetics, the chance that a genetic (inherited) disease present in a family will recur in that family. The concept in general medicine means the chance that an illness we come back again.

Sign: Any objective evidence of disease. Gross blood in the stool is a sign of disease. It can be recognized by the patient, doctor, nurse, or others. In contrast, a symptom is, by its nature, subjective. Abdominal pain is a symptom. It is something only the patient can know.
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Skin: The skin is the body's outer covering. It protects us against heat and light, injury, and infection. It regulates body temperature and stores water, fat, and vitamin D. Weighing about 6 pounds, the skin is the body's largest organ. It is made up of two main layers; the outer epidermis and the inner dermis.

Stage: As regards cancer , the extent of a cancer, especially whether the disease has spread from the original site to other parts of the body. See also: Staging .
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Surgery: The word "surgery" has multiple meanings. It is the branch of medicine concerned with diseases and conditions which require or are amenable to operative procedures. Surgery is the work done by a surgeon. By analogy, the work of an editor wielding his pen as a scalpel is s form of surgery. A surgery in England (and some other countries) is a physician's or dentist's office.
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Symptom: Any subjective evidence of disease. Anxiety, lower back pain, and fatigue are all symptoms. They are sensations only the patient can perceive. In contrast, a sign is objective evidence of disease. A bloody nose is a sign. It is evident to the patient, doctor, nurse and other observers.

Therapy: The treatment of disease .
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Tissue: A tissue in medicine is not like a piece of tissue paper. It is a broad term that is applied to any group of cells that perform specific functions. A tissue in medicine need not form a layer. Thus,

• The bone marrow is a tissue;
• Connective tissue consists of cells that make up fibers in the framework supporting other body tissues; and
• Lymphoid tissue is the part of the body's immune system that helps protect it from bacteria and other foreign entities.

Tonometry: A standard eye test that determines the fluid pressure inside the eye. Increased pressure is a possible sign of glaucoma , a common and potentially very serious eye problem if not detected and treated promptly. It is recommended that adults over age 40 have tonometry for glaucoma every 3 to 5 years by having their eye pressures measured.
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Visual acuity: The clarity or clearness of the vision, a measure of how well a person sees. The ability to distinguish details and shapes of objects; also called central vision.
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Visual acuity test: This test measures how well you see at various distances. It is the familiar eye chart test.
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Vitamin A: Vitamin A is retinol. Carotene compounds (found, for example, in egg yolk, butter and cream) are gradually converted by the body to vitamin A (retinol). A form of vitamin A called retinal is responsible for transmitting light sensation in the retina of the eye.
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Vitamin C: An essential nutrient found mainly in fruits and vegetables. The body requires vitamin C to form and maintain bones, blood vessels, and skin.
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Vitamin D: A steroid vitamin which promotes the intestinal absorption and metabolism of calcium and phosphorus . Under normal conditions of sunlight exposure, no dietary supplementation is necessary because sunlight promotes adequate vitamin D synthesis in the skin. Deficiency can lead to bone deformity ( rickets ) in children and bone weakness (osteomalacia) in adults.
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Vitamins: The word "vitamin" was coined in 1911 by the Warsaw-born biochemist Casimir Funk (1884-1967). At the Lister Institute in London, Funk isolated a substance that prevented nerve inflammation (neuritis) in chickens raised on a diet deficient in that substance. He named the substance "vitamine" because he believed it was necessary to life and it was a chemical amine. The "e" at the end was later removed when it was recognized that vitamins need not be amines.
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Zinc: A mineral essential to the body, zinc is a constituent of many enzymes that permit chemical reactions to proceed at normal rates. It is involved in the manufacture of protein (protein synthesis) and in cell division. Zinc is also a constituent of insulin , and is concerned with the sense of smell.
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Zinc oxide: A form of zinc that has antispasmodic qualities.
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From the Doctors at MedicineNet.com

Visual Field Test - Read about visual field testing and vision tests (Amsler grid, Humphrey-Zeiss and Goldman perimetry tests) for glaucoma and macular degeneration detection. Source:MedicineNet Tonometry - Get the facts on tonometry, a method for measuring intraocular pressure (IOP) and detecting glaucoma. Learn how tonometry is performed and the equipment that's used during the procedure. Source:MedicineNet Anemia - Learn what Anemia is, detection, symptoms, causes, and treatment Source:MedicineNet Read 46 more Macular Degeneration (Age-Related Type) related articles ... Omega-3 Foods May Lower Eye Disease Risk Doctors See How Cancer Drug Can Damage Kidneys Hormone Replacement May Cut Risk for Age-Linked Eye Disease Laser Won't Stop AMD Vision Loss Age-Related Eye Disease on the Increase Macular Degeneration Drug Adds Vision Study Finds Potential Cause of Age-Related Macular Degeneration Age-Related Macular Degeneration Doubles Heart Attack and Stroke Risk Corneal Transplants Can Carry Infection Risk Inflammatory Substance May Boost Eye Trouble