Table of Contents
- Lung cancer facts
- What is lung cancer?
- How common is lung cancer?
- What causes lung cancer?
- What causes lung cancer? (Part 2)
- What causes lung cancer? (Part 3)
- What are the types of lung cancer?
- What are lung cancer symptoms and signs?
- How do health-care professionals diagnose lung cancer?
- How do health-care professionals diagnose lung cancer? (Continued)
- How do health-care professionals determine lung cancer staging?
- What is the treatment for lung cancer?
- What is the treatment for lung cancer? (Part 2)
- What is the treatment for lung cancer? (Part 3)
- What is the prognosis of lung cancer?
- Is it possible to prevent lung cancer?
Quick GuideLung Cancer Symptoms, Stages, Treatments
What are lung cancer symptoms and signs?
Symptoms of lung cancer are varied depending upon where and how widespread the tumor is. Warning signs of lung cancer are not always present or easy to identify. Lung cancer may not cause pain or other symptoms in some cases. A person with lung cancer may have the following kinds of symptoms:
- No symptoms: In up to 25% of people who get lung cancer, the cancer is first discovered on a routine chest X-ray or CT scan as a solitary small mass sometimes called a coin lesion, since on a two-dimensional X-ray or CT scan, the round tumor looks like a coin. These patients with small, single masses often report no symptoms at the time the cancer is discovered.
- Symptoms related to the cancer: The growth of the cancer and invasion of lung tissues and surrounding tissue may interfere with breathing, leading to symptoms such as cough, shortness of breath, wheezing, chest pain, and coughing up blood (hemoptysis). If the cancer has invaded nerves, for example, it may cause shoulder pain that travels down the outside of the arm (called Pancoast syndrome) or paralysis of the vocal cords leading to hoarseness. Invasion of the esophagus may lead to difficulty swallowing (dysphagia). If a large airway is obstructed, collapse of a portion of the lung may occur and cause infections (abscesses, pneumonia) in the obstructed area.
- Symptoms related to metastasis: Lung cancer that has spread to the bones may produce excruciating pain at the sites of bone involvement. Cancer that has spread to the brain may cause a number of neurologic symptoms that may include blurred vision, headaches, seizures, or symptoms of stroke such as weakness or loss of sensation in parts of the body.
- Paraneoplastic symptoms: Lung cancers frequently are accompanied by symptoms that result from production of hormone-like substances by the tumor cells. These paraneoplastic syndromes occur most commonly with SCLC but may be seen with any tumor type. A common paraneoplastic syndrome associated with SCLC is the production of a hormone called adrenocorticotrophic hormone (ACTH) by the cancer cells, leading to oversecretion of the hormone cortisol by the adrenal glands (Cushing's syndrome). The most frequent paraneoplastic syndrome seen with NSCLC is the production of a substance similar to parathyroid hormone, resulting in elevated levels of calcium in the bloodstream.
- Nonspecific symptoms: Nonspecific symptoms seen with many cancers, including lung cancers, include weight loss, weakness, and fatigue. Psychological symptoms such as depression and mood changes also are common.
When should one consult a doctor?
One should consult a health-care professional if he or she develops the symptoms associated with lung cancer, in particular, if they have
- a new persistent cough or worsening of an existing chronic cough,
- blood in the sputum,
- persistent bronchitis or repeated respiratory infections,
- chest pain,
- unexplained weight loss and/or fatigue,
- breathing difficulties such as shortness of breath or wheezing. Continue Reading
Amos, C.I., et al. "Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1." Nature Genetics 40.5 (2008): 616-622.
United States. Centers for Disease Control and Prevention. "Lung Cancer." Nov. 6, 2014. <http://www.cdc.gov/cancer/lung/>.
United States. National Cancer Institute. "Lung Cancer." <http://www.cancer.gov/cancertopics/types/lung>.
2. Getty Images/Science Photo Library
3. iStock/ MedicineNet / American Cancer Society
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10. National Cancer Institute / Ytrottier/ iStock
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