Table of Contents
- Lung cancer facts
- What is lung cancer?
- How common is lung cancer?
- What causes lung cancer?
- What causes lung cancer? (Part 2)
- What causes lung cancer? (Part 3)
- What are the types of lung cancer?
- What are lung cancer symptoms and signs?
- How do health-care professionals diagnose lung cancer?
- How do health-care professionals diagnose lung cancer? (Continued)
- How do health-care professionals determine lung cancer staging?
- What is the treatment for lung cancer?
- What is the treatment for lung cancer? (Part 2)
- What is the treatment for lung cancer? (Part 3)
- What is the prognosis of lung cancer?
- Is it possible to prevent lung cancer?
Quick GuideLung Cancer Symptoms, Stages, Treatment
What is the prognosis of lung cancer?
The prognosis of lung cancer refers to the chance for cure or prolongation of life (survival) and is dependent upon where the cancer is located, the size of the cancer, the presence of symptoms, the type of lung cancer, and the overall health status of the patient.
SCLC has the most aggressive growth of all lung cancers, with a median survival time of only two to four months after diagnosis when untreated. (That is, by two to four months, half of all patients have died.) However, SCLC is also the type of lung cancer most responsive to radiation therapy and chemotherapy. Because SCLC spreads rapidly and is usually disseminated at the time of diagnosis, methods such as surgical removal or localized radiation therapy are less effective in treating this type of lung cancer. When chemotherapy is used alone or in combination with other methods, survival time can be prolonged four- to fivefold; however, of all patients with SCLC, only 5%-10% are still alive five years after diagnosis. Most of those who survive have limited-stage SCLC before treatment.
In non-small cell lung cancer (NSCLC), the most important prognostic factor is the stage (extent of spread) of the tumor at the time of diagnosis. Results of standard treatment are generally poor in all but the smallest of cancers that can be surgically removed. However, in stage I cancers that can be completely removed surgically, five-year survival approaches 75%. Radiation therapy can produce a cure in a small minority of patients with NSCLC and leads to relief of symptoms in most patients. In advanced-stage disease, chemotherapy offers modest improvements in survival although rates of overall survival are poor.
The overall prognosis for lung cancer is poor when compared with some other cancers. Survival rates for lung cancer are generally lower than those for most cancers, with an overall five-year survival rate for lung cancer of about 17% compared to 65% for colon cancer, 91% for breast cancer, 81% for bladder cancer, and over 99% for prostate cancer.
Is it possible to prevent lung cancer?
Cessation of smoking and eliminating exposure to tobacco smoke is the most important measure that can prevent lung cancer. Many products, such as nicotine gum, nicotine sprays, or nicotine inhalers, may be helpful to people trying to quit smoking. Minimizing exposure to passive smoking also is an effective preventive measure. Using a home radon test kit can identify and allow correction of increased radon levels in the home. Methods that allow early detection of cancers, such as the helical low-dose CT scan, also may be of value in the identification of small cancers that can be cured by surgical resection and prevented from becoming widespread, incurable, metastatic cancer. Continue Reading
Amos, C.I., et al. "Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1." Nature Genetics 40.5 (2008): 616-622.
United States. Centers for Disease Control and Prevention. "Lung Cancer." Nov. 6, 2014. <http://www.cdc.gov/cancer/lung/>.
United States. National Cancer Institute. "Lung Cancer." <http://www.cancer.gov/cancertopics/types/lung>.
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3. iStock/ MedicineNet / American Cancer Society
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10. National Cancer Institute / Ytrottier/ iStock
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