lubiprostone, Amitiza (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

DOSING: The recommended dose of lubiprostone is 24 mcg taken orally twice daily with food and water

DRUG INTERACTIONS: Lubiprostone has no known drug interactions.

PREGNANCY: Use of lubiprostone in pregnant women has not been adequately evaluated during pregnancy.

NURSING MOTHERS: It is not known whether lubiprostone is excreted in human milk.

SIDE EFFECTS: The most common side effects of lubiprostone are nausea and diarrhea. Nausea was reduced when lubiprostone was administered with food. Other side effects include headache, frequent bowel movements, fecal incontinence, flatulence, decreased appetite and rash. Some patients may experience shortness of breath.

Reference: FDA Prescribing Information

Last Editorial Review: 4/2/2012

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