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February 10, 2012

losartan and hydrochlorothiazide, Hyzaar

GENERIC NAME: losartan and hydrochlorothiazide

BRAND NAME: Hyzaar

DRUG CLASS AND MECHANISM: Hyzaar is a combination of losartan (Cozaar) and hydrochlorothiazide and is used for treating high blood pressure. For more information, please see the information for each of the two component drugs.

GENERIC AVAILABLE: Yes

PRESCRIPTION: Yes

PREPARATIONS: Tablets containing 50mg of losartan and 12.5mg of hydrochlorothiazide.

STORAGE: Tablets should be stored at room temperature, between 15-30°C (59-86°F) and protected from excessive light and humidity. They should be kept in a tightly-closed, light-resistant container.

PRESCRIBED FOR: Hyzaar is used to treat patients with high blood pressure. It has been shown to reduce the risk of stroke in patients with high blood pressure and left ventricular hypertrophy except in African-American patients.

DOSING: Hyzaar usually is taken once or twice daily.

DRUG INTERACTIONS: Please see the information for each of the component drugs.

PREGNANCY: Please see the information for each of the component drugs in regard to pregnancy.

NURSING MOTHERS: Please see the information for each of the component drugs.

SIDE EFFECTS: Please see the information for each of the component drugs.

Reference: FDA Prescribing Information


Last Editorial Review: 5/27/2005




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  • Related Diseases & Conditions

    • High Blood Pressure
      • High blood pressure, also known as hypertension, is a repeatedly elevated blood pressure exceeding 140 over 90 mmHg -- a systolic pressure above 140 with a diastolic pressure above 90. There are two causes of high blood pressure, primary and secondary. Primary high blood pressure is much more common that secondary and its basic causes or underlying defects are not always known. It is known that a diet high in salt increases the risk for high blood pressure, as well as high cholesterol. Genetic factors are also a primary cause. Secondary high blood pressure is generally caused by another condition such as renal hypertension, tumors, and other conditions. Treatment for high blood pressure is generally lifestyle changes and if necessary, diet.
    • Stroke
      • A stroke results from impaired oxygen delivery to brain cells via the bloodstream. A stroke is also referred to as a CVA, or cerebrovascular incident. Symptoms of stroke include: sudden numbness or weakness of the face, arm or leg. Sudden confusion, trouble speaking or understanding. Sudden trouble seeing in one or both eyes, sudden trouble walking, dizziness, or loss of balance, and/or sudden severe headache with no known cause. A TIA, or transient ischemic attack is a short-lived temporary impairment of the brain caused by loss of blood supply. Stroke is a medical emergency.
    • High Blood Pressure Treatment
      • High blood pressure (hypertension) means high pressure (tension) in the arteries. Treatment for high blood pressure include lifestyle modifications (alcohol, smoking, coffee, salt, diet, exercise), drugs and medications such as ACE inhibitors, angiotensin receptor blockers, beta blockers, diuretics, calcium channel blockers (CCBs), alpha blockers, clonidine, minoxidil, and Exforge.
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losartan and hydrochlorothiazide, Hyzaar

What is high blood pressure?

High blood pressure or hypertension means high pressure (tension) in the arteries. Arteries are vessels that carry blood from the pumping heart to all the tissues and organs of the body. High blood pressure does not mean excessive emotional tension, although emotional tension and stress can temporarily increase blood pressure. Normal blood pressure is below 120/80; blood pressure between 120/80 and 139/89 is called "pre-hypertension", and a blood pressure of 140/90 or above is considered high.

The top number, which is the systolic blood pressure, corresponds to the pressure in the arteries as the heart contracts and pumps blood into the arteries. The bottom number, the diastolic pressure, represents the pressure in the arteries as the heart relaxes after the contraction. The diastolic pressure reflects the lowest pressure to which the arteries are exposed.

An elevation of the systolic and/or diastolic blood pressure incre...

Read the High Blood Pressure Treatment article »







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