- 10 Common Allergy Triggers Slideshow Pictures
- Take the Quiz on Allergies
- Nasal Allergy Relief Products Slideshow
- What is loratadine, and how does it work (mechanism of action)?
- What brand names are available for loratadine?
- Is loratadine available as a generic drug?
- Do I need a prescription for loratadine?
- What are the uses for loratadine?
- What are the side effects of loratadine?
- What is the dosage for loratadine?
- Which drugs or supplements interact with loratadine?
- Is loratadine safe to take if I'm pregnant or breastfeeding?
- What else should I know about loratadine?
What is loratadine, and how does it work (mechanism of action)?
Loratadine is a long-acting, non-sedating antihistamine that is used for the treatment of allergies. Histamine is a chemical that causes many of the signs and symptoms of an allergy. Histamine is released from histamine-storing cells (mast cells) and attaches to other cells that have receptors for histamine on their surfaces. Histamine stimulates the cells to release chemicals that produce effects that we associate with allergy, including welts, itching, and tissue swelling. Loratadine blocks one type of histamine receptor (the H1 receptor) and thus prevents activation of cells with H1 receptors by histamine. Unlike some antihistamines, loratadine does not enter the brain from the blood and, therefore, does not cause drowsiness when taken at recommended doses. The FDA approved loratadine in April 1993.
What brand names are available for loratadine?
Claritin, Claritin RediTabs, Alavert, Claritin Hives Relief, Children's Claritin, and others
Is loratadine available as a generic drug?
GENERIC AVAILABLE: Yes
Do I need a prescription for loratadine?
What are the uses for loratadine?
- Loratadine is used for the relief of nasal and non-nasal symptoms of seasonal hay fever (allergic rhinitis).
- It is also used to treat patients with chronic welts (urticaria) and allergic skin rash.
What are the side effects of loratadine?
The most common adverse events with loratadine are:
Nervousness and difficulty sleeping have also been reported.
Quick GuideBad Bugs: Identify Bug Bites From Mosquitos, Spiders and More
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Need help identifying pills and medications?
Use the pill identifier tool on RxList.