loperamide, Imodium A-D, Anti-Diarrheal, TH Anti-Diarrheal, Diamode, Imodium, Kaopectate II, Imodium

  • Medical Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

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GENERIC NAME: loperamide

BRAND NAMES: Imodium A-D, Anti-Diarrheal, TH Anti-Diarrheal, Diamode

DISCONTINUED BRANDS: Imodium, Kaopectate II, Imodium A-D, Maalox Anti-Diarrheal Caplets, Pepto Diarrhea Control

DRUG CLASS AND MECHANISM: Loperamide is a medication that is used for the relief of acute diarrhea and the management of chronic diarrhea in patients with inflammatory bowel disease (Crohn's disease and ulcerative colitis). The effectiveness of loperamide is comparable to another anti-diarrheal, diphenoxylate (Lomotil). Loperamide reduces diarrhea by slowing the forward propulsion of intestinal contents by the intestinal muscles. Although loperamide is related chemically to narcotics such as morphine, it does not have any of narcotics' pain- relieving effects even at high doses. Loperamide was approved by the FDA in 1976.

PRESCRIBED FOR: Loperamide is used for the relief of acute or chronic diarrhea and traveler's diarrhea.

SIDE EFFECTS: Loperamide is generally well-tolerated. The side effects that have been reported during loperamide treatment include:

Medically Reviewed by a Doctor on 2/24/2015

Quick GuideInflammatory Bowel Disease (IBD) Causes, Symptoms, Treatment

Inflammatory Bowel Disease (IBD) Causes, Symptoms, Treatment
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