GENERIC NAME: loperamide
BRAND NAMES: Imodium A-D, Anti-Diarrheal, TH Anti-Diarrheal, Diamode
DISCONTINUED BRANDS: Imodium, Kaopectate II, Imodium A-D, Maalox Anti-Diarrheal Caplets, Pepto Diarrhea Control
DRUG CLASS AND MECHANISM: Loperamide is a medication that is used for the relief of acute diarrhea and the management of chronic diarrhea in patients with inflammatory bowel disease (Crohn's disease and ulcerative colitis). The effectiveness of loperamide is comparable to another anti-diarrheal, diphenoxylate (Lomotil). Loperamide reduces diarrhea by slowing the forward propulsion of intestinal contents by the intestinal muscles. Although loperamide is related chemically to narcotics such as morphine, it does not have any of narcotics' pain- relieving effects even at high doses. Loperamide was approved by the FDA in 1976.
PRESCRIBED FOR: Loperamide is used for the relief of acute or chronic diarrhea and traveler's diarrhea.
SIDE EFFECTS: Loperamide is generally well-tolerated. The side effects that have been reported during loperamide treatment include:
Quick GuideInflammatory Bowel Disease (IBD) Causes, Symptoms, Treatment
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Need help identifying pills and medications?
Use the pill identifier tool on RxList.