Loop Electrosurgical Excision Procedure (LEEP)

  • Medical Author:
    Melissa Conrad Stöppler, MD

    Melissa Conrad Stöppler, MD, is a U.S. board-certified Anatomic Pathologist with subspecialty training in the fields of Experimental and Molecular Pathology. Dr. Stöppler's educational background includes a BA with Highest Distinction from the University of Virginia and an MD from the University of North Carolina. She completed residency training in Anatomic Pathology at Georgetown University followed by subspecialty fellowship training in molecular diagnostics and experimental pathology.

  • Medical Editor: William C. Shiel Jr., MD, FACP, FACR
    William C. Shiel Jr., MD, FACP, FACR

    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

How effective is LEEP?

LEEP has been shown to be comparable to cryotherapy, cold knife conization (surgical removal of the abnormal area), laser ablation (destruction of the abnormal tissue), and laser conization for the removal of abnormal or precancerous tissues of the cervix. Studies have shown that a majority of these methods result in a cure (removal of all the affected tissue).

Further treatment is not typically necessary if all of the abnormal area has been removed, although the precancerous changes may develop again (recur) at a later time. Regular follow-up Pap tests are required following LEEP to evaluate for possible recurrence of the cellular abnormalities.

What are complications of LEEP?

Complications occur in about a small percentage of women undergoing LEEP, including narrowing (stenosis) of the opening of the cervix, greater than expected amounts of bleeding, or infection of the cervix or uterus.

Medically reviewed by Wayne Blocker, MD; Board Certified Obstetrics and Gynecology


Wright, Jason D., M.D. "Patient information: Management of a cervical biopsy with precancerous cells (Beyond the Basics)." Uptodate.com. Updated Jan. 18, 2016.

Medically Reviewed by a Doctor on 9/6/2016

Subscribe to MedicineNet's Cancer Report Newsletter

By clicking Submit, I agree to the MedicineNet's Terms & Conditions & Privacy Policy and understand that I may opt out of MedicineNet's subscriptions at any time.

Health Solutions From Our Sponsors