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Medications and Drugs

GENERIC NAME: lisinopril and hydrochlorothiazide

BRAND NAME: Zestoretic, Prinzide

DRUG CLASS AND MECHANISM: Zestoretic and Prinzide are combinations of two drugs lisinopril and hydrochlorothiazide which are used for treating high blood pressure. For more information please see lisinopril and hydrochlorothiazide.

PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

PREPARATIONS: Tablets: 12.5mg hydrochlorothiazide/10mg lisinopril, 12.5mg hydrochlorothiazide/20mg lisinopril, 25mg hydrochlorothiazide/20mg lisinopril.

STORAGE: Zestoretic and Prinzide should be stored at 59-86°F (15- 30°C) and protected from excessive light and humidity.

PRESCRIBED FOR: Zestoretic and Prinzide are used to treat high blood pressure.

DOSING: The dose of Zestoretic or Prinzide is tailored to the patient's needs.

DRUG INTERACTIONS: Please read the lisinopril and hydrochlorothiazide articles.

PREGNANCY: Please read the lisinopril and hydrochlorothiazide articles.

NURSING MOTHERS: Please read the lisinopril and hydrochlorothiazide articles.

SIDE EFFECTS: Please read the lisinopril and hydrochlorothiazide articles.

Reference: FDA Prescribing Information


Last Editorial Review: 4/3/1999




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lisinopril and hydrochlorothiazide, Zestoretic, Prinzide

What are the kidneys?

The kidneys play key roles in body function, not only by filtering the blood and getting rid of waste products, but also by balancing levels of electrolytes in the body, controlling blood pressure, and stimulating the production of red blood cells.

The kidneys are located in the abdomen toward the back, normally one of each side of the spine. They get their blood supply through the renal arteries directly from the aorta and send blood back to the heart via the renal veins to the vena cava. (The term "renal" is derived from the Latin name for kidney.)

The kidneys have the ability to monitor the amount of body fluid, the concentrations of electrolytes like sodium and potassium, and the acid-base balance of the body. They filter waste products of body metabolism, like urea from protein metabolism and uric acid from DNA breakdown. Two waste products in the blood can be measured: blood urea nitrogen (BUN) and ...

Read the Kidney Failure article »











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