lisinopril, Zestril, Prinivil (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

Nitritoid reactions (symptoms of facial flushing, nausea, vomiting and hypotension) may occur when injectable gold (sodium aurothiomalate), used in the treatment of rheumatoid arthritis, is combined with ACE inhibitors, including lisinopril.

PREGNANCY: Lisinopril should not be taken during pregnancy because fetuses and neonates have died when lisinopril was administered during pregnancy.

NURSING MOTHERS: It is not known whether lisinopril is excreted in breast milk.

SIDE EFFECTS: First doses of lisinopril can cause dizziness due to a drop in blood pressure. Lisinopril can cause nausea, headaches, anxiety, insomnia, drowsiness, nasal congestion, and sexual dysfunction. Like all ACE inhibitors, lisinopril may cause a nonproductive cough that resolves when the drug is discontinued. Lisinopril should be stopped if there are symptoms or signs of an allergic reaction including feelings of swelling of the face, lips, tongue or throat. Severe allergic reactions (anaphylaxis) and hives occasionally occur. Rarely, lisinopril may cause a decrease in red blood cells (anemia), white blood cells (leukopenia), and platelets (thrombocytopenia).

Reference: FDA Prescribing Information


Last Editorial Review: 4/26/2011



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