lisdexamfetamine, Vyvanse (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:



PREPARATIONS: Capsules: 20, 30, 40, 50, 60, and 70 mg

STORAGE: Lisdexamfetamine should be stored at room temperature, 15 C to 30 C (59 F to 86 F), and protected from light.

PRESCRIBED FOR: Lisdexamfetamine is used for the treatment of attention deficit hyperactivity disorder (ADHD).

DOSING: The recommended dose of lisdexamfetamine for adults and pediatric patients ages (6-12) is 30 mg once daily in the morning. Doses may be increased by 10-20 mg/day at weekly intervals. The maximum dose is 70 mg daily. Lisdexamfetamine should not be administered in the afternoon because it may cause insomnia. Capsules may be swallowed whole or the contents may be dissolved in a glass of water.

DRUG INTERACTIONS: Monoamine oxidase inhibitor (MAOIs) antidepressants such as isocarboxazid (Marplan), phenelzine (Nardil), tranylcypromine (Parnate), selegiline (Eldepryl) and procarbazine (Matulane), slow the elimination of amphetamines in the body. This increases the concentration of amphetamines and their effect. This can cause serious elevations in blood pressure (hypertensive crisis) with headaches, other signs of hypertensive crisis, and even fatal reactions. Lisdexamfetamine should not be administered until 14 days after MAOIs have been discontinued in order to allow the effects of the MAOIs to dissipate.

Amphetamines increase the effect of norepinephrine. Combining both drugs may lead to serious cardiovascular toxicity.

Medically Reviewed by a Doctor on 2/4/2014

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Pill Finder Tool

Need help identifying pills and medications?
Use the pill identifier tool on RxList.

Back to Medications Index