lisdexamfetamine, Vyvanse (cont.)
Omudhome Ogbru, PharmD
Omudhome Ogbru, PharmD
Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.
Medical and Pharmacy Editor:
GENERIC AVAILABLE: No
PREPARATIONS: Capsules: 20, 30, 40, 50, 60, and 70 mg
STORAGE: Lisdexamfetamine should be stored at room temperature, 15 C to 30 C (59 F to 86 F), and protected from light.
PRESCRIBED FOR: Lisdexamfetamine is used for the treatment of attention deficit hyperactivity disorder (ADHD).
DOSING: The recommended dose of lisdexamfetamine for adults and pediatric patients ages (6-12) is 30 mg once daily in the morning. Doses may be increased by 10-20 mg/day at weekly intervals. The maximum dose is 70 mg daily. Lisdexamfetamine should not be administered in the afternoon because it may cause insomnia. Capsules may be swallowed whole or the contents may be dissolved in a glass of water.
DRUG INTERACTIONS: Monoamine oxidase inhibitor (MAOIs) antidepressants such as isocarboxazid (Marplan), phenelzine (Nardil), tranylcypromine (Parnate), selegiline (Eldepryl) and procarbazine (Matulane), slow the elimination of amphetamines in the body. This increases the concentration of amphetamines and their effect. This can cause serious elevations in blood pressure (hypertensive crisis) with headaches, other signs of hypertensive crisis, and even fatal reactions. Lisdexamfetamine should not be administered until 14 days after MAOIs have been discontinued in order to allow the effects of the MAOIs to dissipate.
Medically Reviewed by a Doctor on 2/4/2014
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