lisdexamfetamine, Vyvanse

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GENERIC NAME: lisdexamfetamine


DRUG CLASS AND MECHANISM: Lisdexamfetamine is an oral drug used for increasing attention and decreasing impulsiveness and hyperactivity in patients with attention deficit hyperactivity disorder (ADHD). Lisdexamfetamine is a prodrug; after administration it is converted to dextroamphetamine (Adderall) in the intestines and/or liver. The dextroamphetamine, an amphetamine and stimulant for the brain, is responsible for the effect of lisdexamfetamine in ADHD. The mechanism of action of dextroamphetamine in ADHD is unknown, but scientists believe that they may stimulate the nervous system by increasing the release or reducing the inactivation of norepinephrine and dopamine in the brain. Norepinephrine and dopamine are chemicals (neurotransmitters) that nerves use for communicating with each other. The net effect of amphetamines is an increase in the effects of dopamine and norepinephrine. The FDA approved lisdexamfetamine in February 2007.

Medically Reviewed by a Doctor on 2/4/2014

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