Saxenda (liraglutide injection)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

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What brand names are available for liraglutide injection (Saxenda)?

Saxenda

Is liraglutide injection (Saxenda) available as a generic drug?

GENERIC AVAILABLE: No

Do I need a prescription for liraglutide injection (Saxenda)?

Yes

What are the uses for liraglutide injection (Saxenda)?

  • Saxenda is prescribed to help some obese or overweight adults with weight-related medical problems to lose weight and keep the weight off.
  • It is approved for use in combination with a reduced-calorie diet and regular exercise for the long term weight management of adults with an initial body mass index (BMI) of 30 kg/m2 or greater (obese) or 27 kg/m2 or greater (overweight), plus at least one weight related medical condition (for example, high blood pressure, type 2 diabetes, or high blood cholesterol levels).
  • Saxenda is not approved for treatment of diabetes.

What are the side effects of liraglutide injection (Saxenda)?

The most common side effects of Saxenda include:

Saxenda may cause some rare but serious side effects including:

Quick GuideSurprising Reasons for Weight Gain

Surprising Reasons for Weight Gain

What is the dosage for liraglutide injection (Saxenda)?

  • The recommended daily dose of Saxenda for weight management is 3 mg daily.
  • Patients should be started at 0.6 mg per day for 1 week, followed by 0.6 mg dose increments at weekly intervals until a target dose of 3 mg is reached.
  • Saxenda should be discontinued in patients who cannot tolerate the 3 mg, as effectiveness of treatment at lower doses has not been established.
  • Saxenda can be administered once daily at any time of the day, without regard to meals.
  • Saxenda should be injected subcutaneously in the abdomen, thigh, or upper arm.

Which drugs or supplements interact with liraglutide injection (Saxenda)?

: Saxenda delays gastric or stomach emptying and therefore may interfere with the absorption of oral medications taken at the same time as Saxenda.

Is liraglutide injection (Saxenda) safe to take if I'm pregnant or breastfeeding?

:

  • As weight loss during pregnancy offers no benefits to the mother and may cause harm to the fetus. Saxenda should not be used during pregnancy. Saxenda is classified as FDA pregnancy risk category X.
  • It is not known if Saxenda is excreted in breast milk. Due to the lack of safety data, Saxenda should not be used by nursing mothers.

What else should I know about liraglutide injection (Saxenda)?

What preparations of liraglutide injection (Saxenda) are available?

  • Saxenda is available as a solution for subcutaneous injection in pre-filled, disposable, multiple dose pens.
  • Each pen delivers doses of 0.6, 1.2, 1.8, 2.4, or 3 mg (6 mg/ml, 3 ml).
  • Pens come in packs of either 3 or 5.

How should I keep liraglutide injection (Saxenda) stored?

  • Before the first use, Saxenda should be stored in the refrigerator between 36 C to 46 C (2 F to 8 F).
  • After the first use, the pen can be stored at room temperature between 59 F to 86 C (15 F to 30 F) or in the refrigerator between 36 F to 46 C (2 F to 8 F).

REFERENCE: FDA Prescribing Information.

Last Editorial Review: 9/26/2016

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Reviewed on 9/26/2016
References
REFERENCE: FDA Prescribing Information.

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