liraglutide, Victoza (cont.)

Pharmacy Author:

Omudhome Ogbru, PharmD

Omudhome Ogbru, PharmD

Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

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Medical and Pharmacy Editor:

Jay W. Marks, MD

Jay W. Marks, MD

Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

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Combining liraglutide with insulin or drugs that stimulate release of insulin (for example, glyburide) may increase the occurrence of low blood sugar (hypoglycemia). The dose of insulin or the insulin release stimulating drug should be reduced.

There have been reports of acute pancreatitis associated with the use of liraglutide. Patients developing severe, persistent abdominal pain that might be caused by pancreatitis, should seek prompt medical attention. If pancreatitis is suspected, liraglutide should be discontinued and not started again until the presence of pancreatitis has been excluded.

Liraglutide can cause thyroid tumors that occur more frequently at higher doses and with longer duration of treatment. Since liraglutide is a synthetic protein patients may develop antibodies to liraglutide. Liraglutide antibodies may reduce the effectiveness of liraglutide.

REFERENCE: Reference: FDA Prescribing Information

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