Victoza (liraglutide)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

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What brand names are available for liraglutide?

Victoza

Is liraglutide available as a generic drug?

GENERIC AVAILABLE: No

Do I need a prescription for liraglutide?

Yes

What are the uses for liraglutide?

What are the side effects of liraglutide?

  • The most common side effects of Victoza are
  • Combining Victoza with insulin or drugs that stimulate release of insulin (for example, glyburide) may increase the occurrence of low blood sugar (hypoglycemia). The dose of insulin or the insulin release stimulating drug should be reduced.
  • There have been reports of acute pancreatitis associated with the use of Victoza. Patients developing severe, persistent abdominal pain that might be caused by pancreatitis, should seek prompt medical attention. If pancreatitis is suspected, Victoza should be discontinued and not started again until the presence of pancreatitis has been excluded.
  • Victoza can cause thyroid tumors that occur more frequently at higher doses and with longer duration of treatment. Since Victoza is a synthetic protein patients may develop antibodies to Victoza. Victoza antibodies may reduce the effectiveness of Victoza.

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What is the dosage for liraglutide?

  • Victoza is injected under the skin of the abdomen, thigh, or upper arm.
  • Each pre-filled pen can deliver 0.6, 1.2, and 1.8 mg doses. The initial dose is 0.6 mg daily for one week.
  • The initial dose helps the body to build a tolerance to stomach related side effects.
  • Victoza is not effective for controlling blood glucose.
  • After one week the dose is increased to 1.2 mg daily.
  • The maximum dose is 1.8 mg daily.

Which drugs or supplements interact with liraglutide?

  • Victoza slows down transit of food and drugs through the intestine and, therefore, may reduce the absorption of drugs that are taken orally. Although Victoza did not significantly affect the absorption of oral dugs tested in studies, it is still prudent to separate administration of Victoza and oral medications.
  • Combining Victoza with insulin or drugs that stimulate release of insulin (for example, glyburide [Micronase, Diabeta, Glynase, Prestab]) may increase the occurrence of low blood sugar (hypoglycemia). The dose of insulin or the insulin release stimulating drug should be reduced.

Is liraglutide safe to take if I'm pregnant or breastfeeding?

  • There are no adequate studies of Victoza in pregnant women. Most experts agree that insulin is the drug of choice in pregnant women with diabetes.
  • There are no adequate studies of Victoza in nursing mothers, and it is not known whether Victoza is excreted in human breast milk.

What else should I know about liraglutide?

What preparations of liraglutide are available?

Multiple dose pre-filled pen: 18 mg in 3 ml (6 mg/ml)

How should I keep liraglutide stored?

  • Victoza should be refrigerated between 2-8 C (36-46 F) prior to first use.
  • After the first use it can be stored at room temperature 15 C - 30 C (59 F - 86 F) or refrigerated at 2 C - 8 C (36 F - 46 F).

REFERENCE: Reference: FDA Prescribing Information

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See more info: liraglutide on RxList
Reviewed on 9/14/2016
References
REFERENCE: Reference: FDA Prescribing Information

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