liothyronine sodium, Cytomel, Triostat

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GENERIC NAME: liothyronine sodium

BRAND NAME: Cytomel, Triostat

DRUG CLASS AND MECHANISM: Liothyronine sodium is a synthetic (man-made) version of one of the two hormones made by the thyroid gland, triiodothyronine. It is used for treating individuals who are hypothyroid (do not produce enough thyroid hormones). Thyroid hormones increase the metabolism (activity) of all cells in the body. In the fetus, newborn infant and child, thyroid hormones promote growth and development of tissues. In adults, thyroid hormones help to maintain the function of the brain, the use of food by the body, and body temperature. The FDA approved liothyronine in May 1956.

PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

PREPARATIONS: Tablets: 5, 25, and 50 mcg. Injection: 10 mcg/ml

STORAGE: Tablets should be stored at room temperature 20-25 C (68-77°F) and the injectable preparation between 2-8 C (36-46 F )

PRESCRIBED FOR: Liothyronine is used to treat hypothyroidism (low production of thyroid hormone) in adults and children. Prolonged hypothyroidism can result in a condition called myxedema in which patients develop swollen lips, thickened nose, and unusual deposits of material in the skin that are dry and waxy. These deposits also may appear in body tissues other than the skin. Liothyronine also is used for suppressing production of thyroid stimulating hormone in patients with goiters and for testing how well the thyroid gland is functioning.

DOSING: The usual starting dose of liothyronine for treating hypothyroidism is 5 to 25 mcg per day. The dose then is adjusted based on the patient's response and the blood levels of thyroid hormone. Optimal liothyronine doses are different for each patient and vary depending on the patient's age, weight, symptoms, blood levels of thyroid hormone and underlying conditions such as heart disease. Individuals who are hypothyroid will require thyroid hormone for life.




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